| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Mycoplasma pneumoniae reactive IgA |
| species reactivity | Mycoplasma pneumoniae |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available size | 3 mL |
Mycoplasma pneumoniae IgA Control Serum BC127A
$94.00
Summary
- Virion/Serion Diagnostic Kit Control for research use (RUO)
- Mycoplasma pneumoniae IgA Control Serum
- Applications: ELISA
- IgA control serum
- Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
- 3 mL
Mycoplasma pneumoniae IgA Control Serum BC127A
| target relevance |
|---|
| Organism Mycoplasma pneumoniae |
| Structure and strains Mycoplasma pneumoniae is a very small bacterium in the class Mollicutes. It is a human pathogen that causes the disease mycoplasma pneumonia, a form of atypical bacterial pneumonia related to cold agglutinin disease. M. pneumoniae is characterized by the absence of a peptidoglycan cell wall and resulting resistance to many antibacterial agents. The persistence of M. pneumoniae infections even after treatment is associated with its ability to mimic host cell surface composition. |
| Disease Mycoplasma pneumoniae is a worldwide distributed bacterium, which is not surrounded by a rigid cell wall. With a diameter of 0.2 µm, the organism belonging to the class of Mollicutes is one of the smallest human pathogens. It possesses a special organelle that allows attachment to the ciliated epithelium in the respiratory tract. The adhesion is mediated by the highly immunogenic P1-Adhesin (168 kDa). Mycoplasma pneumoniae is the most important causative agent of atypical pneumonia. Despite the high seroprevalence, 10- 15% of all pneumonias are caused by this pathogen. Children and elderly people are particular at risk of Mycoplasma pneumoniae infection, which may manifest with tracheobronchitis, laryngitis, meningitis and otitis media. Furthermore, disorders of the haematopoietic system, the central nervous system and the cardiovascular system can occur. |
| Detection and diagnosis The variety of clinical symptoms of atypical pneumonias and possible causative agents requires a diagnosis that is not exclusively limited to the clinical picture. Serological and direct detection methods can be employed to identify the pathogen and so enable appropriate medical intervention strategies. The direct detection of Mycoplasma pneumoniae by cultivation is difficult and time-consuming. Faster results are achieved by complement fixation tests (CFT). Meanwhile, sensitive and specific ELISA tests are available in order to differentiate between immunoglobulin classes so improving the diagnostic value of the results obtained. |
Data
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
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| BC127A protocol |
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