Immunohistochemistry (IHC) : Human lung adenocarcinoma stained with anti-surfactant antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor glands.

mouse anti-Surfactant monoclonal antibody (ZM124) 6373

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to Surfactant
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1
Control: Lung adenocarcinoma
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6373parent Categories: antibody, Zeta IHC antibodies Tags: anatomy, Lung/Mediastinum Pathology, Surfactant

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Surfactant monoclonal antibody ZM124 6373

antibody
Database link: human P11686
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Lung adenocarcinoma
Immunogen Recombinant fragment (around aa 241-336) of human SFTPD protein
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Homo sapiens SFTPC Surfactant protein C
Protein names Surfactant protein C
Alternative names Pulmonary surfactant-associated protein C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5
Gene names SFTPC
Function Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces
Subcellular location Secreted, extracellular space, surface film
Involvement in disease Pulmonary surfactant metabolism dysfunction 2 A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Keywords 3D-structure, Alternative splicing, Direct protein sequencing, Disease variant, Disulfide bond, Gaseous exchange, Lipoprotein, Palmitate, Proteomics identification, Reference proteome, Secreted, Surface film
Sequence MDVGSKEVLMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVVVVLIVVVIVGALLMGLHM SQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTGLVVYDYQQLLIAYKPAPGTC CYIMKIAPESIPSLEALTRKVHNFQMECSLQAKPAVPTSKLGQAEGRDAGSAPSGGDPAF LGMAVSTLCGEVPLYYI
UniProt accession: P11686

Data

Human lung adenocarcinoma stained with anti-surfactant antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor glands.

FAQ & Publications

Frequently Asked Questions

What species does the mouse anti-Surfactant monoclonal antibody (ZM124) specifically react with?

This antibody is reactive with human species.

For which application is the mouse anti-Surfactant monoclonal antibody (ZM124) validated?

It is suitable and validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded tissues.

What are the recommended storage conditions for this antibody to maintain its stability?

For short-term storage, keep the antibody at 2-8°C. For long-term storage, it should be kept at -20°C, avoiding repeated freeze/thaw cycles.

What is the host and isotype of the mouse anti-Surfactant monoclonal antibody (ZM124)?

The antibody is produced in mouse and is of the IgG1 isotype.

What immunogen was used to generate this monoclonal antibody?

The immunogen is a recombinant fragment of the human SFTPD protein, approximately amino acids 241-336.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.