Immunohistochemistry (IHC) : Human lymph node stained with anti-CD7antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of perifollicular T-cells cells.

mouse anti-CD7 monoclonal antibody (ZM213) 6108

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to CD7
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1
Control: Tonsil or lymph node
Visualization: Membrane
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6108parent Category: antibody Tags: anatomy, CD7, Hematopathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-CD7 monoclonal antibody ZM213 6108

antibody
Database link: human P09564
Tested applications IHC
Recommended dilutions Concentrated 1:50-100
Application Notes Positive control: Tonsil or lymph node
Immunogen Recombinant human full-length CD7 protein
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Protein names T-cell antigen CD7 (GP40) (T-cell leukemia antigen) (T-cell surface antigen Leu-9) (TP41) (CD antigen CD7)
Gene names CD7,CD7
Mass 25409Da
Function FUNCTION: Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726). {ECO:0000269\|PubMed:10652336, ECO:0000269\|PubMed:1709867, ECO:0000269\|PubMed:7506726}.
Subellular location SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Tissues TISSUE SPECIFICITY: Expressed on T-cells and natural killer (NK) cells and their precursors. {ECO:0000269\|PubMed:1709867, ECO:0000269\|PubMed:7506726}.
Structure SUBUNIT: Interacts with SECTM1. {ECO:0000269\|PubMed:10652336}.
Target Relevance information above includes information from UniProt accession: P09564
The UniProt Consortium

Data

Human lymph node stained with anti-CD7antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of perifollicular T-cells cells.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.