| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
mouse anti-CD7 monoclonal antibody (ZM213) 6108
Price range: $160.00 through $528.00
Antibody summary
- Mouse monoclonal to CD7
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG1
- Control: Tonsil or lymph node
- Visualization: Membrane
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
mouse anti-CD7 monoclonal antibody ZM213 6108
| target relevance |
|---|
| Homo sapiens CD7 T-cell antigen CD7 |
| Protein names T-cell antigen CD7 |
| Alternative names GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41 |
| Gene names CD7 |
| Function Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726) |
| Subcellular location Membrane |
| Structure Interacts with SECTM1 |
| Keywords Adaptive immunity, Disulfide bond, Glycoprotein, Immunity, Immunoglobulin domain, Lipoprotein, Membrane, Palmitate, Proteomics identification, Receptor, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix |
| Sequence MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLR QLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEV NVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALP AALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAACVVYEDMSHSRCNTLSSPNQYQ |
| UniProt accession: P09564 |
Data
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| Human lymph node stained with anti-CD7antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of perifollicular T-cells cells. |
FAQ & Publications
Frequently Asked Questions
What species does the mouse anti-CD7 monoclonal antibody (ZM213) specifically react with?
This antibody specifically reacts with human CD7 protein, making it suitable for studies involving human samples.
What are the recommended storage conditions for maintaining the stability of this antibody?
For short-term storage, keep the antibody at 2-8°C. For long-term storage, it should be kept at -20°C, and repeated freeze/thaw cycles should be avoided to preserve antibody integrity.
Which applications and sample types is this mouse anti-CD7 antibody validated for?
The antibody is validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded human tissue samples, with tonsil or lymph node tissue recommended as positive controls.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| IHC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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