Cytomegalovirus IgM Control Serum BC109M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Cytomegalovirus (CMV) IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC109M Categories: control serum, Virion/Serion kits Tags: Cytomegalovirus, ELISA control serum, IgM

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Cytomegalovirus reactive IgM
species reactivity	Cytomegalovirus
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Cytomegalovirus IgM Control Serum BC109M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Cytomegalovirus Avidity Reagent (B109AVID) Cytomegalovirus Antigen (BA109VS) Cytomegalovirus Avidity Control(BR109AVID) Cytomegalovirus Antigen (BA109VS) Cytomegalovirus IgG Control Serum (BC109G) Cytomegalovirus IgM Control Serum (BC109M) Cytomegalovirus IgG ELISA Kit (ESR109G) Cytomegalovirus IgM ELISA Kit (ESR109M)

target relevance

human antibody anti-Cytomegalovirus (CMV)

Cytomegalovirus (CMV)

Description
Virus that causes cytomegalovirus infection and congenital CMV disease

Structure
Cytomegalovirus (CMV), also known as Human herpesvirus 5 (HHV-5), is an enveloped, double-stranded DNA virus belonging to the genus Cytomegalovirus within the family Herpesviridae. The virus possesses an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing multiple glycoproteins involved in host cell entry. CMV has one of the largest genomes among human viruses and is capable of infecting a wide variety of cell types including epithelial cells, endothelial cells, fibroblasts, monocytes, and leukocytes. Following primary infection, CMV establishes lifelong latency, primarily within cells of the myeloid lineage, and may periodically reactivate, particularly in immunocompromised individuals. CMV is widely distributed throughout the world, and a large proportion of adults show evidence of prior infection.

Diagnosis
The diagnosis of cytomegalovirus infection is performed through serological, molecular, and virological methods. Detection of CMV-specific IgM and IgG antibodies by ELISA or other immunoassays is commonly used to determine recent or past infection. Molecular methods such as quantitative polymerase chain reaction (PCR) are highly sensitive and are widely used to detect and monitor CMV DNA in blood, urine, saliva, cerebrospinal fluid, and other clinical specimens. Antigenemia assays and viral culture may also be employed in selected clinical settings. In pregnant women and immunocompromised patients, laboratory testing is particularly important for assessing active infection, viral load, and risk of disease progression.

Symptoms
Most cytomegalovirus infections in healthy individuals are asymptomatic or cause mild, self-limiting illness resembling infectious mononucleosis, characterized by fever, fatigue, malaise, sore throat, lymphadenopathy, and muscle aches. Following primary infection, the virus remains latent and may reactivate later in life. In immunocompromised individuals, including transplant recipients, cancer patients, and people with advanced HIV infection, CMV can cause severe disease involving the lungs, liver, gastrointestinal tract, retina, and central nervous system. Congenital CMV infection is a major cause of birth defects and may result in hearing loss, vision impairment, developmental delays, microcephaly, seizures, and other neurological complications. CMV remains one of the most significant opportunistic viral pathogens worldwide.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application for the Cytomegalovirus IgM Control Serum BC109M?

The Cytomegalovirus IgM Control Serum BC109M is designed for use as a control serum in ELISA applications, specifically for indirect and quantitative assays targeting Cytomegalovirus reactive IgM.

How should the Cytomegalovirus IgM Control Serum BC109M be stored to maintain its stability?

The Cytomegalovirus IgM Control Serum BC109M should be stored at 2-8°C to preserve its stability and ensure optimal performance in assays.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC109M protocol

Documents

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Cytomegalovirus IgM Control Serum BC109M

Data

FAQ & Publications

Protocols

Documents

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Reviews

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