Enterovirus IgM Control Serum BC133M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Enterovirus IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC133M Categories: control serum, Virion/Serion kits Tags: ELISA control serum, Enterovirus, IgM

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Enterovirus reactive IgM
species reactivity	Enterovirus
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Enterovirus IgM Control Serum BC133M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Enterovirus Antigen (BA133VS01) Enterovirus IgA Control Serum (BC133A) Enterovirus IgG Control Serum (BC133G) Enterovirus IgM Control Serum (BC133M) Enterovirus IgA ELISA Kit (ESR133A) Enterovirus IgG ELISA Kit (ESR133G) Enterovirus IgM ELISA Kit (ESR133M)

target relevance

human antibody anti-Enterovirus

Enterovirus

Description
Group of viruses that cause respiratory, neurological, gastrointestinal, and systemic infections

Structure
Enteroviruses are non-enveloped, positive-sense, single-stranded RNA viruses belonging to the genus Enterovirus within the family Picornaviridae. The genus comprises numerous human pathogens, including polioviruses, coxsackieviruses, echoviruses, rhinoviruses, and enterovirus A71, among others. Enteroviruses possess an icosahedral capsid that protects the viral genome and contributes to remarkable environmental stability and resistance to many disinfectants. Transmission occurs primarily through the fecal-oral route, respiratory secretions, and direct contact with contaminated surfaces. Following infection, the viruses typically replicate in the gastrointestinal tract and upper respiratory tract before disseminating through the bloodstream to other tissues and organs. Enteroviruses are among the most common viral pathogens worldwide and are responsible for a broad spectrum of clinical diseases ranging from mild febrile illness to severe neurological disease.

Diagnosis
The diagnosis of enterovirus infection is performed through molecular, virological, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic technique due to its high sensitivity and specificity and can detect enteroviral RNA in respiratory specimens, stool samples, blood, cerebrospinal fluid, and tissue samples. Viral culture may be used in specialized laboratories but has largely been replaced by molecular testing. Serological assays may assist in epidemiological investigations and retrospective diagnosis but are less commonly used in routine clinical practice. Laboratory confirmation is particularly important in cases involving meningitis, encephalitis, myocarditis, neonatal sepsis-like illness, or outbreak investigations.

Symptoms
Enterovirus infections produce a wide range of clinical manifestations depending on the infecting strain and affected organ systems. Many infections are asymptomatic or result in mild febrile illness characterized by fever, fatigue, headache, sore throat, and gastrointestinal symptoms. Common clinical syndromes include hand, foot and mouth disease, herpangina, viral meningitis, encephalitis, myocarditis, pericarditis, conjunctivitis, and respiratory tract infections. Certain enteroviruses, such as poliovirus and enterovirus D68, can cause severe neurological disease including acute flaccid paralysis. Neonates, immunocompromised individuals, and patients with cardiac or neurological involvement are at increased risk of severe disease. While most infections are self-limiting, some may result in long-term neurological or cardiac complications.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Enterovirus IgM Control Serum BC133M?

The Enterovirus IgM Control Serum BC133M is designed for use as a control serum in ELISA assays, specifically for indirect and quantitative detection of enterovirus reactive IgM antibodies.

How should the Enterovirus IgM Control Serum BC133M be stored to maintain its stability?

The serum should be stored at 2-8°C to ensure proper preservation and maintain its effectiveness for research use.

Is the Enterovirus IgM Control Serum BC133M compatible with specific ELISA kits?

Yes, this control serum is ready-to-use and pre-diluted for compatibility with SERION ELISA classic and SERION ELISA antigen assays.

Which species and target does the Enterovirus IgM Control Serum BC133M specifically react with?

This control serum is reactive to IgM antibodies targeting enterovirus species, which are positive-sense single-stranded RNA viruses affecting humans and mammals.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC133M protocol

Documents

#
CP0118	Safety Data Sheet	QC certificate

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Enterovirus IgM Control Serum BC133M

Data

FAQ & Publications

Protocols

Documents

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Reviews

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