| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Chikungunya Virus reactive IgM |
| species reactivity | Chikungunya virus |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available sizes | 96 tests |
Chikungunya Virus IgM ELISA Kit ESR148M
$334.00
RF-Absorbent Z200 for use with IgM ELISA kits
Did you know that RF Absorbent Z200 is recommended for the removal of IgM rheumatoid factors from serum and plasma samples prior to the detection of pathogen-specific IgM? Consider adding it to your cart for improved signal specificity. For more details, please refer to the IgM ELISA kit protocol.
- Virion/Serion Diagnostic Kit for research use (RUO)
- Chikungunya Virus IgM ELISA Kit
- Suitable for IgM detection
- Ready-to-use
- 96 tests
Chikungunya Virus IgM ELISA Kit ESR148M
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| Assay type Indirect ELISA | ||||||||||||||||||
| Research area Infectious Disease | ||||||||||||||||||
| Sample type Serum, plasma, whole blood | ||||||||||||||||||
| Notes Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results. | ||||||||||||||||||
Components
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| Storage Store at 2-8°C. | ||||||||||||||||||
| Associated products Chikungunya Glycoprotein E2 Antigen (BA148R1) Chikungunya Glycoprotein E1 Antigen (BA148R2) Chikungunya Glycoprotein E1 (A226V) Antigen (BA148R3) Chikungunya Virus Human IgG Assay Control (BC148G) Chikungunya Virus Human IgM Assay Control (BC148M) Chikungunya Virus IgG ELISA Kit (ESR148G) Chikungunya Virus IgM ELISA Kit (ESR148M) |
| target relevance |
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| Organism Chikungunya Virus |
| Structure and strains Chikungunya is an infection caused by the Chikungunya virus (CHIKV). The disease was first identified in 1952 in Tanzania and named based on the Kimakonde words for "to become contorted". Symptoms include fever and joint pain. These typically occur two to twelve days after exposure. Other symptoms may include headache, muscle pain, joint swelling, and a rash. Symptoms usually improve within a week; however, occasionally the joint pain may last for months or years. The risk of death is around 1 in 1,000. The very young, old, and those with other health problems are at risk of more severe disease. |
| Disease The chikungunya virus is a member of the alphavirus genus. It is also classified as arbovirus due to vector-dependent transmission by mosquitos. The enveloped virus carries structural glycoproteins E1-E3 that are particular immunogenic. Within the viral capsid several non-structure proteins and a ss-(+)-RNA genome are embedded. The virus is the causative agent of chikungunya fever that is characterized by fever, joint pain and joint swelling, rash, and unspecific flu-like symptoms. The symptoms usually appear within a period of one to two weeks but mainly appear during the first week post infection. The disease is characterized by a biphasic course with an initial stage with high virus load (5-7 days) and a convalescent stage without viremia. A chronic course of disease that goes along with severe joint pain might occur. In rare cases neurological disorders like Guillain-Barre syndrome and meningoencephalitis, also with lethal courses, were described. |
| Detection and diagnosis The diagnosis is mainly based on direct pathogen detection or serological methods. Within the early phases virus detection by RT-PCR is the method of choice. After the onset of immune responses viremia will drop leading to reduced sensitivity of direct detection methods. Achieving this stage demonstration of specific antibodies should be used for diagnosis. Due to persistence of IgG and to lesser extent IgM antibody serology allows for retrospective evaluation. |
Data
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
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| ESR148M protocol |
Documents
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