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Gynecological Pathology

Gynecological Pathology: IHC in gynecological pathology helps identify markers related to ovarian, endometrial, and cervical cancers. Hormone receptor status (estrogen and progesterone) and markers like p16 and Ki-67 are used to assess the malignancy and potential for targeted therapy, while distinguishing between benign and malignant lesions.

	target	type	reactivity	applications
6039	BRG1/SMARC4	rabbit monoclonal (ZR390)	human	IHC
6043	CA 125/ MUC16	mouse monoclonal (ZM53)	human	IHC
6210	HCG	rabbit monoclonal (ZR362)	human	IHC
6303	p16INK4a	mouse monoclonal (G175-405)	human	IHC
6304	p16INK4a	mouse monoclonal (MX007)	human	IHC
6305	p16INK4a	mouse monoclonal (JC2)	human	IHC
6306	p16INK4a	rabbit monoclonal (ZR407)	human	IHC
6313	p57Kip2	mouse monoclonal (KP10)	human	IHC
6314	p57Kip2	rabbit monoclonal (ZR230)	human	IHC
6337	PLAP	mouse monoclonal (ZM161)	human	IHC
6338	PLAP	rabbit monoclonal (ZR441)	human	IHC
6341	Podoplanin	mouse monoclonal (D2-40)	human	IHC
6342	Podoplanin	rabbit monoclonal (ZR442)	human	IHC
6370	Stathmin	rabbit monoclonal (ZR389)	human	IHC
6404	WT-1	mouse monoclonal (6F-H2)	human	IHC

IHC with antibody [6210] : Formalin-fixed, paraffin-embedded human placenta stained with anti-HCG-beta antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of trophoblasts

IHC with antibody [6303] : High grade cervical intraepithelial neoplasia (CINIII) stained with anti-p16 antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear and cytoplasmic staining of dysplastic cells, whereas the normal squamoujs mucosa is negative.

IHC with antibody [6304] : Invasive cervical squamous cell carcinoma stained with anti-p16 antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear and cytoplasmic staining of carcinoma cells.

ICC