Immunohistochemistry (IHC) : Human mesothelioma stained with anti-calretinin antibody using peroxidase-conjugate and DAB chromogen. Note nuclear/cytoplasmic staining of mesothelioma cells.

mouse anti-Calretinin monoclonal antibody (ZM85) 6052

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to Calretinin
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1
Control: Mesothelioma
Visualization: Cytoplasmic and nuclear
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6052parent Category: antibody Tags: anatomy, Calretinin, Lung/Mediastinum Pathology

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Calretinin monoclonal antibody ZM85 6052

antibody
Database link: human P22676
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Mesothelioma
Immunogen Recombinant human Calretinin (Calbindin 2) protein fragment (around aa23-242)
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Protein names Calretinin (CR) (29 kDa calbindin)
Gene names CALB2,CALB2 CAB29
Protein family Calbindin family
Mass 31540Da
Function FUNCTION: Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways (PubMed:2001709). Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory (By similarity). During embryonic development, it facilitates neuronal differentiation and maturation (By similarity). {ECO:0000250\|UniProtKB:P47728, ECO:0000250\|UniProtKB:Q08331, ECO:0000269\|PubMed:2001709}.
Subellular location SUBCELLULAR LOCATION: Synapse {ECO:0000250\|UniProtKB:Q08331}. Cell projection, dendrite {ECO:0000250\|UniProtKB:Q08331}. Note=Located in dendrioles, small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell. {ECO:0000250\|UniProtKB:Q08331}.
Tissues TISSUE SPECIFICITY: Brain.
Target Relevance information above includes information from UniProt accession: P22676
The UniProt Consortium

Data

Human mesothelioma stained with anti-calretinin antibody using peroxidase-conjugate and DAB chromogen. Note nuclear/cytoplasmic staining of mesothelioma cells.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.