Yersinia IgM Control Serum BC138M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Yersinia IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC138M Categories: control serum, Virion/Serion kits Tags: ELISA control serum, IgM, Yersinia

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Yersinia reactive IgM
species reactivity	Yersinia
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Yersinia IgM Control Serum BC138M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Yersinia enterocolitica o-8 YOP (Yersinia outer proteins) Antigen (BA13808VS) Yersinia enterocolitica o-9 YOP (Yersinia outer proteins) Antigen (BA13809VS) Yersinia enterocolitica o-3 YOP (Yersinia outer proteins) Antigen (BA138VS) Yersinia IgA Control Serum (BC138A) Yersinia IgG Control Serum (BC138G) Yersinia IgM Control Serum (BC138M) Yersinia IgA ELISA Kit (ESR138A) Yersinia IgG ELISA Kit (ESR138G) Yersinia IgM ELISA Kit (ESR138M)

target relevance

human antibody anti-Yersinia

Yersinia

Description
Bacterial genus that causes yersiniosis, plague, and other zoonotic infections

Structure
Yersinia is a genus of Gram-negative, facultatively anaerobic coccobacilli belonging to the family Yersiniaceae. Members of the genus are widely distributed in nature and can infect a variety of mammalian hosts. The most clinically important species include Yersinia enterocolitica, Yersinia pseudotuberculosis, and Yersinia pestis. Y. enterocolitica and Y. pseudotuberculosis are primarily enteric pathogens that cause gastrointestinal disease, while Y. pestis is the causative agent of plague. Yersinia species possess numerous virulence factors, including adhesins, invasins, secretion systems, and plasmid-encoded proteins that enable invasion of host tissues and evasion of immune responses. The bacteria can survive and replicate within host cells and are capable of causing both localized and systemic infections.

Diagnosis
The diagnosis of Yersinia infection is performed through microbiological, molecular, and serological methods. Isolation of the organism from stool, blood, lymph node aspirates, or other clinical specimens remains the definitive diagnostic method. Selective culture techniques may be required, particularly for Yersinia enterocolitica. Polymerase chain reaction (PCR) assays provide rapid and sensitive detection of Yersinia DNA and are increasingly used in clinical laboratories. Serological tests, including ELISA-based assays, may be used to detect antibodies against Yersinia antigens and can be particularly useful in cases of post-infectious complications or epidemiological investigations. For plague caused by Yersinia pestis, rapid diagnosis is essential to enable prompt treatment and public health intervention.

Symptoms
Clinical manifestations of Yersinia infection vary depending on the infecting species. Yersinia enterocolitica and Yersinia pseudotuberculosis commonly cause yersiniosis, characterized by fever, abdominal pain, diarrhea, nausea, and vomiting. In older children and adults, infection may mimic acute appendicitis due to mesenteric lymphadenitis. Reactive arthritis and erythema nodosum can occur as post-infectious complications. Yersinia pestis causes plague, which may present as bubonic plague with painful swollen lymph nodes (buboes), septicemic plague with bloodstream infection, or pneumonic plague involving severe respiratory disease. Without prompt treatment, systemic Yersinia infections can progress to severe sepsis, organ failure, and death.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Yersinia IgM Control Serum BC138M?

The Yersinia IgM Control Serum BC138M is primarily used as an IgM control serum in ELISA assays, specifically designed for research use with SERION ELISA classic and SERION ELISA antigen assays.

How should the Yersinia IgM Control Serum BC138M be stored to maintain its stability?

This control serum should be stored at a temperature between 2 to 8 degrees Celsius to preserve its stability and efficacy.

Is the Yersinia IgM Control Serum BC138M ready to use or does it require dilution?

The serum is provided ready-to-use and is pre-diluted for direct application in SERION ELISA classic and SERION ELISA antigen assays.

Which species' antibodies does the Yersinia IgM Control Serum BC138M specifically target?

The serum targets IgM antibodies reactive to Yersinia, particularly species within the Yersinia enterocolitica group.

What is the assay type compatible with Yersinia IgM Control Serum BC138M for detecting antibodies?

The serum is compatible with indirect and quantitative ELISA assay types for the detection of Yersinia-reactive IgM antibodies.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC138M protocol

Documents

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Yersinia IgM Control Serum BC138M

Data

FAQ & Publications

Protocols

Documents

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Reviews

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