Yersinia enterocolitica O:8 YOP (Yersinia outer proteins) Antigen BA13808VS

$1,515.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Yersinia enterocolitica O:8 YOP (Yersinia outer proteins) Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA13808VS Category: Infectious disease proteins Tags: antigen, Yersinia

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Yersinia enterocolitica O:8 YOP (Yersinia outer proteins)
species reactivity	Yersinia
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Yersinia enterocolitica O:8 YOP (Yersinia outer proteins) Antigen BA13808VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Yersinia enterocolitica o-8 YOP (Yersinia outer proteins) Antigen (BA13808VS) Yersinia enterocolitica o-9 YOP (Yersinia outer proteins) Antigen (BA13809VS) Yersinia enterocolitica o-3 YOP (Yersinia outer proteins) Antigen (BA138VS) Yersinia IgA Control Serum (BC138A) Yersinia IgG Control Serum (BC138G) Yersinia IgM Control Serum (BC138M) Yersinia IgA ELISA Kit (ESR138A) Yersinia IgG ELISA Kit (ESR138G) Yersinia IgM ELISA Kit (ESR138M)

target relevance
Yersinia
Description Bacterial genus that causes yersiniosis, plague, and other zoonotic infections
Structure Yersinia is a genus of Gram-negative, facultatively anaerobic coccobacilli belonging to the family Yersiniaceae. Members of the genus are widely distributed in nature and can infect a variety of mammalian hosts. The most clinically important species include Yersinia enterocolitica, Yersinia pseudotuberculosis, and Yersinia pestis. Y. enterocolitica and Y. pseudotuberculosis are primarily enteric pathogens that cause gastrointestinal disease, while Y. pestis is the causative agent of plague. Yersinia species possess numerous virulence factors, including adhesins, invasins, secretion systems, and plasmid-encoded proteins that enable invasion of host tissues and evasion of immune responses. The bacteria can survive and replicate within host cells and are capable of causing both localized and systemic infections.
Diagnosis The diagnosis of Yersinia infection is performed through microbiological, molecular, and serological methods. Isolation of the organism from stool, blood, lymph node aspirates, or other clinical specimens remains the definitive diagnostic method. Selective culture techniques may be required, particularly for Yersinia enterocolitica. Polymerase chain reaction (PCR) assays provide rapid and sensitive detection of Yersinia DNA and are increasingly used in clinical laboratories. Serological tests, including ELISA-based assays, may be used to detect antibodies against Yersinia antigens and can be particularly useful in cases of post-infectious complications or epidemiological investigations. For plague caused by Yersinia pestis, rapid diagnosis is essential to enable prompt treatment and public health intervention.
Symptoms Clinical manifestations of Yersinia infection vary depending on the infecting species. Yersinia enterocolitica and Yersinia pseudotuberculosis commonly cause yersiniosis, characterized by fever, abdominal pain, diarrhea, nausea, and vomiting. In older children and adults, infection may mimic acute appendicitis due to mesenteric lymphadenitis. Reactive arthritis and erythema nodosum can occur as post-infectious complications. Yersinia pestis causes plague, which may present as bubonic plague with painful swollen lymph nodes (buboes), septicemic plague with bloodstream infection, or pneumonic plague involving severe respiratory disease. Without prompt treatment, systemic Yersinia infections can progress to severe sepsis, organ failure, and death.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application for the Yersinia enterocolitica O:8 YOP Antigen BA13808VS?

The Yersinia enterocolitica O:8 YOP Antigen BA13808VS is primarily used for detecting IgA, IgG, and IgM antibodies in ELISA assays, providing indirect and quantitative measurement.

How should this antigen be stored to maintain its stability?

This antigen should be stored at -65°C or lower and should be protected from repeated freeze-thaw cycles to preserve its integrity for up to 10 years from the date of manufacture under recommended conditions.

Is the Yersinia enterocolitica O:8 YOP Antigen reactive with other Yersinia species?

The antigen is specifically reactive with Yersinia enterocolitica, as indicated in its species reactivity profile.

What is the form and quantity of the Yersinia enterocolitica O:8 YOP Antigen supplied?

The antigen is supplied as a liquid form with a lot-specific concentration and is available in a 1 mg quantity per vial.

Can this antigen be used to differentiate between acute and chronic yersiniosis?

Yes, the antigen facilitates sensitive and specific ELISA testing to quantitatively determine IgG, IgM, and IgA antibodies, which helps differentiate between acute and chronic yersiniosis and assess post-infectious complications.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.