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Yersinia IgA ELISA kit-SERION classic ESR138A

$398.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Yersinia IgA ELISA Kit
Suitable for IgA detection
Ready-to-use
96 tests

SKU: ESR138A Category: Virion/Serion kits Tags: ELISA, IgA, Yersinia

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Yersinia reactive IgA
species reactivity	Yersinia
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Yersinia IgA ELISA Kit ESR138A

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgA-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Yersinia enterocolitica o-8 YOP (Yersinia outer proteins) Antigen (BA13808VS)
Yersinia enterocolitica o-9 YOP (Yersinia outer proteins) Antigen (BA13809VS)
Yersinia enterocolitica o-3 YOP (Yersinia outer proteins) Antigen (BA138VS)
Yersinia IgA Control Serum (BC138A)
Yersinia IgG Control Serum (BC138G)
Yersinia IgM Control Serum (BC138M)
Yersinia IgA ELISA Kit (ESR138A)
Yersinia IgG ELISA Kit (ESR138G)
Yersinia IgM ELISA Kit (ESR138M)

target relevance

human antibody anti-Yersinia

Yersinia

Description
Bacterial genus that causes yersiniosis, plague, and other zoonotic infections

Structure
Yersinia is a genus of Gram-negative, facultatively anaerobic coccobacilli belonging to the family Yersiniaceae. Members of the genus are widely distributed in nature and can infect a variety of mammalian hosts. The most clinically important species include Yersinia enterocolitica, Yersinia pseudotuberculosis, and Yersinia pestis. Y. enterocolitica and Y. pseudotuberculosis are primarily enteric pathogens that cause gastrointestinal disease, while Y. pestis is the causative agent of plague. Yersinia species possess numerous virulence factors, including adhesins, invasins, secretion systems, and plasmid-encoded proteins that enable invasion of host tissues and evasion of immune responses. The bacteria can survive and replicate within host cells and are capable of causing both localized and systemic infections.

Diagnosis
The diagnosis of Yersinia infection is performed through microbiological, molecular, and serological methods. Isolation of the organism from stool, blood, lymph node aspirates, or other clinical specimens remains the definitive diagnostic method. Selective culture techniques may be required, particularly for Yersinia enterocolitica. Polymerase chain reaction (PCR) assays provide rapid and sensitive detection of Yersinia DNA and are increasingly used in clinical laboratories. Serological tests, including ELISA-based assays, may be used to detect antibodies against Yersinia antigens and can be particularly useful in cases of post-infectious complications or epidemiological investigations. For plague caused by Yersinia pestis, rapid diagnosis is essential to enable prompt treatment and public health intervention.

Symptoms
Clinical manifestations of Yersinia infection vary depending on the infecting species. Yersinia enterocolitica and Yersinia pseudotuberculosis commonly cause yersiniosis, characterized by fever, abdominal pain, diarrhea, nausea, and vomiting. In older children and adults, infection may mimic acute appendicitis due to mesenteric lymphadenitis. Reactive arthritis and erythema nodosum can occur as post-infectious complications. Yersinia pestis causes plague, which may present as bubonic plague with painful swollen lymph nodes (buboes), septicemic plague with bloodstream infection, or pneumonic plague involving severe respiratory disease. Without prompt treatment, systemic Yersinia infections can progress to severe sepsis, organ failure, and death.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Yersinia IgA ELISA Kit ESR138A?

The Yersinia IgA ELISA Kit ESR138A is compatible with serum, plasma, and whole blood samples for the detection of Yersinia reactive IgA antibodies.

How should the Yersinia IgA ELISA Kit ESR138A be stored to maintain its stability?

The kit components should be stored at 2-8°C to ensure proper stability and performance.

What is the assay type and detection method used in the Yersinia IgA ELISA Kit ESR138A?

This kit uses an indirect and quantitative ELISA assay to detect IgA antibodies reactive to Yersinia antigens.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR138A protocol

Documents

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Yersinia IgA ELISA kit-SERION classic ESR138A

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

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