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Tick-Borne Encephalitis Virus IgG ELISA kit-SERION <i>classic</i> ESR112G - Image 2

Tick-Borne Encephalitis Virus IgG ELISA kit-SERION classic ESR112G

$364.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Tick-Borne Encephalitis Virus (TBEV) IgG ELISA Kit
Suitable for IgG detection
Ready-to-use
96 tests

SKU: ESR112G Category: Virion/Serion kits Tags: ELISA, IgG, Tick-Borne Encephalitis Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Tick-Borne Encephalitis Virus reactive IgG
species reactivity	Tick-Borne Encephalitis Virus
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Tick-Borne Encephalitis Virus IgG ELISA Kit ESR112G

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgG-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
FSME/TBE (Tick-Borne Encephalitis) Virus (Premium) Antigen (BA112VS)
FSME/TBE (Tick-Borne Encephalitis) Virus Antigen (BA112VSL)
Tick-Borne Encephalitis Virus IgG Control Serum (BC112G)
Tick-Borne Encephalitis Virus IgM Control Serum (BC112M)
Tick-Borne Encephalitis Virus IgG ELISA Kit (ESR112G)
Tick-Borne Encephalitis Virus IgM ELISA Kit (ESR112M)

target relevance

human antibody anti-Tick-Borne Encephalitis Virus (TBE/FSME)

Tick-Borne Encephalitis Virus (TBE/FSME)

Description
Virus that causes tick-borne encephalitis (TBE/FSME)

Structure
Tick-borne encephalitis virus (TBEV), also known as FSME virus (Frühsommer-Meningoenzephalitis virus), is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Flavivirus within the family Flaviviridae. The virus is closely related to other medically important flaviviruses, including West Nile virus, Yellow fever virus, Dengue virus, and Zika virus. TBEV is maintained in nature through transmission cycles involving ixodid ticks, primarily Ixodes ricinus and Ixodes persulcatus, and a variety of wild mammalian hosts. Three major subtypes are recognized: European, Siberian, and Far Eastern. Human infection typically occurs through the bite of an infected tick, although transmission may also occur through the consumption of unpasteurized milk or dairy products from infected animals. The virus is neurotropic and can invade the central nervous system, resulting in severe neurological disease.

Diagnosis
The diagnosis of tick-borne encephalitis virus infection is performed through serological and molecular methods. Detection of TBEV-specific IgM and IgG antibodies using ELISA is the primary laboratory approach and is considered highly sensitive and specific during the neurological phase of disease. Confirmation may be obtained using virus neutralization assays. Molecular detection by reverse transcription polymerase chain reaction (RT-PCR) may identify viral RNA during the early viremic phase but is often less useful after neurological symptoms develop because viremia is typically transient. Cerebrospinal fluid analysis frequently demonstrates pleocytosis and elevated protein concentrations in patients with central nervous system involvement. Accurate laboratory diagnosis is essential because clinical symptoms overlap with those of other viral and bacterial neurological infections.

Symptoms
Tick-borne encephalitis virus infection frequently follows a biphasic course. After an incubation period of approximately seven to fourteen days, the initial phase is characterized by nonspecific flu-like symptoms including fever, fatigue, headache, muscle aches, malaise, and nausea. Following a symptom-free interval, a second phase may occur in which the virus affects the central nervous system, resulting in meningitis, encephalitis, meningoencephalitis, or myelitis. Neurological manifestations may include severe headache, neck stiffness, confusion, impaired consciousness, tremors, paralysis, seizures, and cognitive dysfunction. While many infections remain asymptomatic or mild, severe disease can result in long-term neurological sequelae or death, particularly among older adults and patients infected with more virulent viral subtypes.

Data

FAQ & Publications

Frequently Asked Questions

What sample types are compatible with the Tick-Borne Encephalitis Virus IgG ELISA Kit ESR112G?

The ESR112G kit is compatible with serum, plasma, and whole blood samples for detecting Tick-Borne Encephalitis Virus reactive IgG antibodies.

How should the Tick-Borne Encephalitis Virus IgG ELISA Kit ESR112G be stored to maintain stability?

The kit should be stored at 2-8°C to ensure the stability of all components and reliable assay performance.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR112G protocol

Documents

#
EQ0167	Safety Data Sheet	QC certificate

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Tick-Borne Encephalitis Virus IgG ELISA kit-SERION classic ESR112G

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

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