| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-MUC-6 monoclonal antibody (ZR437) 6272
$160.00 – $528.00
Antibody summary
- Rabbit monoclonal to MUC-6
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: Stomach
- Visualization: Cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-MUC-6 monoclonal antibody ZR437 6272
| target relevance |
|---|
| Protein names Mucin-6 (MUC-6) (Gastric mucin-6) |
| Mass 257051Da |
| Function May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. |
| Subellular location Secreted. |
| Tissues Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct. |
| Structure Multimer; disulfide-linked. |
| Post-translational modification PTM: O-glycosylated. |
| Domain DOMAIN 43..214; /note="VWFD 1"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"; DOMAIN 302..357; / |
| Target Relevance information above includes information from UniProt accession: Q6W4X9 |
| The UniProt Consortium |
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