| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
rabbit anti-LH monoclonal antibody (ZR173) 6242
Price range: $160.00 through $528.00
Antibody summary
- Rabbit monoclonal to LH
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG
- Control: Pituitary
- Visualization: Cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
rabbit anti-LH monoclonal antibody ZR173 6242
| target relevance |
|---|
| Homo sapiens LHB Lutropin subunit beta |
| Protein names Lutropin subunit beta |
| Alternative names Luteinizing hormone subunit beta |
| Gene names LHB |
| Protein family Belongs to the glycoprotein hormones subunit beta family |
| Function Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids |
| Subcellular location Secreted |
| Structure Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin |
| Involvement in disease Hypogonadotropic hypogonadism 23 with or without anosmia A form of hypogonadotropic hypogonadism, a group of disorders characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. HH23 male patients have normal sexual differentiation, reduced or absent Leydig cells, reduced or absent spermatogenesis, and absence of spontaneous puberty. Female patients exhibit normal pubertal development and menarche, followed by oligomenorrhea and anovulatory secondary amenorrhea. |
| Keywords Direct protein sequencing, Disease variant, Disulfide bond, Glycoprotein, Hormone, Hypogonadotropic hypogonadism, Proteomics identification, Reference proteome, Secreted, Signal |
| Sequence MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPT MMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDC GGPKDHPLTCDHPQLSGLLFL |
| UniProt accession: P01229 |
Data
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| Formalin-fixed, paraffin-embedded human pituitary stained with anti-FSH antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of glandular cells |
FAQ & Publications
Frequently Asked Questions
What species does the rabbit anti-LH monoclonal antibody (ZR173) specifically react with?
This antibody specifically reacts with human tissues.
For which application is the rabbit anti-LH monoclonal antibody (ZR173) validated and recommended?
It is validated and recommended for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded tissues.
How should the rabbit anti-LH monoclonal antibody (ZR173) be stored to maintain stability?
For short-term storage, keep the antibody at 2-8°C; for long-term storage, store at -20°C while avoiding freeze/thaw cycles.
What is the recommended dilution range when using the concentrated form of this rabbit anti-LH monoclonal antibody for IHC?
The recommended dilution for the concentrated antibody is between 1:100 and 1:200 for immunohistochemistry.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| IHC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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