Immunohistochemistry (IHC) : Human liver infected by hepatitis B virus stained with anti-HBsAg antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of infected hepatocytes.

rabbit anti-HBsAg monoclonal antibody (ZR393) 6209

$160.00 – $528.00

Antibody summary

Rabbit monoclonal to Hepatitis B Virus (HBV) HBsAg
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG
Control: Hepatitis B infected liver
Visualization: Cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

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SKU: 6209parent Category: antibody Tags: anatomy, HBsAg, Infectious Markers

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

rabbit anti-HBsAg monoclonal antibody ZR393 6209

antibody
https://www.uniprot.org/uniprotkb/Q76R62/
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Hepatitis B infected liver
Immunogen Recombinant full-length HBsAg protein
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control Rabbit polyclonal - Isotype Control

target relevance
Protein names Large envelope protein (L glycoprotein) (L-HBsAg) (LHB) (Large S protein) (Large surface protein) (Major surface antigen)
Gene names S,S
Protein family Orthohepadnavirus major surface antigen family
Mass 43669Da
Function #N/A
Subellular location #N/A
Structure SUBUNIT: [Isoform L]: In its internal form (Li-HBsAg), interacts with the capsid protein and with the isoform S. Interacts with host chaperone CANX. {ECO:0000250\|UniProtKB:P03141}.; SUBUNIT: [Isoform M]: Associates with host chaperone CANX through its pre-S2 N glycan; this association may be essential for isoform M proper secretion. {ECO:0000250\|UniProtKB:P03141}.; SUBUNIT: [Isoform S]: Interacts with isoform L. Interacts with the antigens of satellite virus HDV (HDVAgs); this interaction is required for encapsidation of HDV genomic RNA. {ECO:0000250\|UniProtKB:P03141}.
Post-translational modification PTM: Isoform M is N-terminally acetylated by host at a ratio of 90%, and N-glycosylated by host at the pre-S2 region. {ECO:0000250\|UniProtKB:P03138, ECO:0000255\|HAMAP-Rule:MF_04075}.; PTM: Myristoylated. {ECO:0000255\|HAMAP-Rule:MF_04075}.
Domain #N/A
Biotechnology BIOTECHNOLOGY: Systematic vaccination of individuals at risk of exposure to the virus has been the main method of controlling the morbidity and mortality associated with hepatitis B. The first hepatitis B vaccine was manufactured by the purification and inactivation of HBsAg obtained from the plasma of chronic hepatitis B virus carriers. The vaccine is now produced by recombinant DNA techniques and expression of the S isoform in yeast cells. The pre-S region do not seem to induce strong enough antigenic response.
Target Relevance information above includes information from UniProt accession: Q76R62
The UniProt Consortium

Data

Human liver infected by hepatitis B virus stained with anti-HBsAg antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of infected hepatocytes.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.