Parainfluenza Virus Type 3 Control Antigen BA1263VS

$944.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Parainfluenza Virus Type 3 Control Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA1263VS Category: Infectious disease proteins Tags: antigen, Parainfluenza Virus, protein

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Parainfluenza Virus Type 3
species reactivity	Parainfluenza Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Parainfluenza Virus Type 3 Control Antigen BA1263VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Parainfluenza Virus Type 1 Antigen (BA1261VS) Parainfluenza Virus Type 2 Antigen (BA1262VS) Parainfluenza Virus Type 3 Control Antigen (BA1263VS) Parainfluenza Virus Human IgA Assay Control (BC126A) Parainfluenza Virus Human IgG Assay Control (BC126G) Parainfluenza Virus IgA ELISA Kit (ESR126A) Parainfluenza Virus IgG ELISA Kit (ESR126G)

target relevance
Parainfluenza Virus
Description Virus that causes upper and lower respiratory tract infections, including croup
Structure Human parainfluenza viruses (HPIVs) are enveloped, negative-sense, single-stranded RNA viruses belonging to the family Paramyxoviridae. Four major types, HPIV-1, HPIV-2, HPIV-3, and HPIV-4, are recognized as important human respiratory pathogens. The viral envelope contains hemagglutinin-neuraminidase (HN) and fusion (F) glycoproteins that facilitate attachment to and entry into host respiratory epithelial cells. Human parainfluenza viruses are distributed worldwide and are among the most common causes of respiratory tract infections in infants and young children, although reinfections frequently occur throughout life. HPIV-1 and HPIV-2 are particularly associated with croup, while HPIV-3 is a major cause of bronchiolitis and pneumonia. The viruses are transmitted through respiratory droplets, direct contact with respiratory secretions, and contaminated surfaces.
Diagnosis The diagnosis of parainfluenza virus infection is performed through molecular, antigen detection, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic method due to its high sensitivity and specificity and is commonly included in multiplex respiratory pathogen panels. Viral RNA can be detected in nasopharyngeal swabs, throat swabs, and other respiratory specimens. Antigen detection assays and direct immunofluorescence tests may provide more rapid results but generally have lower sensitivity than molecular methods. Viral culture may be used in specialized laboratories, while serological assays are primarily utilized for epidemiological studies and research purposes. Laboratory confirmation is particularly useful in hospitalized patients, immunocompromised individuals, and outbreak investigations.
Symptoms Parainfluenza virus infections typically develop following an incubation period of approximately two to seven days. Clinical manifestations vary according to patient age, immune status, and viral type. Common symptoms include fever, runny nose, nasal congestion, sore throat, cough, hoarseness, and malaise. In young children, parainfluenza viruses are a leading cause of croup, characterized by a distinctive barking cough, inspiratory stridor, and respiratory distress due to inflammation of the upper airway. Lower respiratory tract involvement may result in bronchiolitis, bronchitis, or pneumonia, particularly in infants, elderly individuals, and immunocompromised patients. While most infections are self-limiting, severe respiratory disease may occur in vulnerable populations and occasionally requires hospitalization.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Parainfluenza Virus Type 3 Control Antigen BA1263VS?

The Parainfluenza Virus Type 3 Control Antigen BA1263VS is primarily used as a control antigen for the detection of IgA, IgG, and IgM antibodies in ELISA assays, supporting indirect and quantitative assay types for research use.

How should the Parainfluenza Virus Type 3 Control Antigen BA1263VS be stored to maintain its stability?

This control antigen should be stored at -65°C or lower to ensure stability, and repeated freeze-thaw cycles should be avoided. It is recommended to sonicate the antigen before use and it has a shelf life of 10 years from the date of manufacture under the recommended storage conditions.

Is the Parainfluenza Virus Type 3 Control Antigen BA1263VS specific to any species or virus strain?

The antigen is reactive to Parainfluenza Virus, specifically Parainfluenza Virus Type 3, which is one of the human parainfluenza viruses belonging to the Paramyxoviridae family. It is designed for use with this viral target in research applications.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.