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mouse anti-Adenovirus monoclonal antibody (20-11 & 2-6) 6013

$160.00$528.00

Antibody summary

  • Mouse monoclonal to Adenovirus
  • Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
  • Reacts with: Human
  • Isotype:IgG1
  • Control: Adenovirus infected tissue
  • Visualization: Organisms
  • 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
SKU: 6013parent Category: Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
host

mouse

isotype

IgG1

clonality

monoclonal

concentration

concentrate, predilute

applications

IHC

reactivity

human

available size

0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-Adenovirus monoclonal antibody 20&11 & 2&6 6013

antibody
Tested applications
IHC
Recommended dilutions
As directed
Immunogen
Adenovirus
Size and concentration
7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form
liquid
Storage Instructions
2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity
affinity purified
Clonality
monoclonal
Isotype
IgG1
Compatible secondaries
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486
goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854
goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706
goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716
goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control
Mouse monoclonal IgG1 - Isotype Control
target relevance
Structure
Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953.

They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system.
Biotechnology
Direct and indirect detection methods are used for the diagnosis of Adenovirus infectons. Due to the variety of clinical symptoms, which may be caused by Adenoviruses, serological investigations have become important for the differential diagnosis of respiratory tract infections.
Involvement in disease
Adenoviruses are dsDNA viruses with icosahedral symmetry and a diameter of 90 to 100 nm. They belong to the family of Adenoviridae and were discovered in isolates from adenoids. Approximately 50 subtypes have been identified as human pathogens, with subtypes 1 to 8, 40 and 41 occuring most frequently.

Adenoviruses are responsible for a wide range of different diseases. In most cases, infections present with ocular, respiratory or gastrointestinal manifestations. Additionally, urethral infections, as well as hepatitis and meningoencephalitis are possible. Keratoconjunctivitis epidemica is a particularly significant ocular nosocomial infection. Patients with weakened immune systems are particularly susceptible to serious complications following infection with Adenoviruses, e.g. Acute Respiratory Distress Syndrome (ARDS). Sequelae may include persistent bronchitis, joint pain, dilative cardiomyopathy, type 1 diabetes and hearing deficits.

Data

Human lung stained with anti-Adenovirus antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of adenovirus infected pneumocytes .
Human lung stained with anti-Adenovirus antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of adenovirus infected pneumocytes .

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

relevant to this product
IHC

Documents

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