Immunohistochemistry (IHC) : Human lung infected with toxoplasma gondii stained with anti-toxoplasma gondii antibody using peroxidase-conjugate and DAB chromogen. Note positive staining of organisms..

rabbit anti-Toxoplasma gondii monoclonal antibody Poly 6389

$160.00 – $528.00

Antibody summary

Rabbit monoclonal to Toxoplasma gondii
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG
Control: Toxoplasma Gondii infected tissue
Visualization: Organisms
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

SKU: 6389parent Category: antibody Tag: Toxoplasma gondii

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

rabbit anti-Toxoplasma gondii monoclonal antibody Poly 6389

antibody

Tested applications IHC
Recommended dilutions As directed
Immunogen Toxoplasma gondii
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control Rabbit polyclonal - Isotype Control

target relevance
Structure Toxoplasma gondii is a parasitic protozoan (specifically an apicomplexan) that causes toxoplasmosis. Found worldwide, T. gondii is capable of infecting virtually all warm-blooded animals,: 1 but felids are the only known definitive hosts in which the parasite may undergo sexual reproduction.
Biotechnology The diagnosis of toxoplasmosis is based on clinical findings and serological investigations. ELISA tests are recommended for the demonstration of IgG and IgM antibodies. Screening for Toxoplasma infections during pregnancy is of significant importance in prenatal care. The transmission of Toxoplasma gondii via the transplacental route has been observed in all stages of pregnancy, although the risk of a prenatal transmission as well as the outcome of infection depends on the stage of pregnancy. The risk of an infection of the unborn child via transplacental transmission is limited to seronegative women who acquire a primary infection during pregnancy. IgM antibodies directed against Toxoplasma gondii can persist for months after infection. Therefore, the determination of the IgG antibody avidity allows for differentiation of primary from past infections.
Involvement in disease Toxoplasma gondii is an eucaryotic protozoa of the sporozoa group. The obligatory intracellular parasite is distributed worldwide. Following oral uptake of the parasite, e. g. with contaminated food, the organism penetrates the gut and enters the reticuloendothelial system. Due to the following hematogenous dissemination, Toxoplasma gondii is able to infect many different organs and tissues. Approximately 50% of infections with Toxoplasma gondii proceed subclinically. The remainder demonstrate only unspecific symptoms such as low fever, exhaustion, headache as well as muscle and joint pain after an incubation period of one to three weeks. A minority of patients suffer from high fever up to 39°C and swelling of lymph nodes. In 1% of infected children and young adults complications such as myocarditis, meningitis or pneumonia are reported. After recovery, Toxoplasma gondii persists in infected tissues by forming cysts.

Data

Human lung infected with toxoplasma gondii stained with anti-toxoplasma gondii antibody using peroxidase-conjugate and DAB chromogen. Note positive staining of organisms..

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.