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Herpes simplex Virus 1 IgG ELISA Kit ESR1051G

$325.00

Summary

  • Virion/Serion Diagnostic Kit for research use (RUO)
  • Herpes simplex Virus 1 IgG ELISA Kit
  • Suitable for IgG detection
  • Ready-to-use
  • 96 tests
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Herpes simplex Virus 1 reactive IgG

species reactivity

Herpes Simplex Virus

applications

ELISA

assay type

Indirect & quantitative

available sizes

96 tests

Available product – Herpes simplex Virus 1 IgG ELISA Kit ESR1051G

kit
Assay type
Indirect ELISA
Research area
Infectious Disease
Sample type
Serum, plasma, whole blood
Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.
Components
Break apart microtiter test strips each with antigen coated single wells8 x 12 (96 Total)
Standard serum (ready-to-use)2 x 2 mL
Negative control serum (ready-to-use)2 mL
Anti-human-IgG-conjugate (ready-to-use)13 mL
Washing solution concentrate (sufficient for 1000ml)33.3 mL
Dilution buffer2 x 50 mL
Stopping solution15 mL
Substrate (ready-to-use)13 mL
Quality control certificate with standard curve and evaluation table1
Storage
Store at 2-8°C.
Associated products
Herpes simplex Virus 1 Glycoprotein G Antigen (BA1051RVS-G)
Herpes simplex Virus 1 Antigen (BA1051VS)
Herpes Simplex Virus 1 gP IgG Control Serum (BC1051G)
Herpes Simplex Virus 1 IgM Control Serum (BC1051M)
Herpes simplex Virus 1 IgG ELISA Kit (ESR1051G)
Herpes simplex Virus 1 IgM ELISA Kit (ESR1051M)
target relevance
Organism
Herpes Simplex Virus 1/2
Structure and strains
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.

As of 2016, about 67% of the world population under the age of 50 had HSV-1. In the United States, about 47.8% and 11.9% are estimated to have HSV-1 and HSV-2, respectively, though actual prevalence may be much higher. Because it can be transmitted through any intimate contact, it is one of the most common sexually transmitted infections.
Disease
Herpes Simplex Virus 1 (HSV 1) and Herpes Simplex Virus 2 (HSV 2) are DNA viruses belonging to the family of Herpesviridae. They occur globally. In industrialized countries the seroprevalence amounts to 50% in the second decade of life, in adults even up to 90% for HSV 1 and 10 to 15% for HSV 2.

The transmission of Herpes Simplex Virus 1 occurs by contact with contaminated salivary or smear infection. Herpes Simplex Virus 2 is transmitted via contact with infected mucosal skin. Primary HSV 1 infections process inapparently in 90% of cases. 10% of infected persons suffer from inflammations of cornea and conjunctiva or show the characteristic herpes vesiculation at the lips. These pustular eruptions can spread on eczematous skin with life-threatening effects. Other complications are encephalitis or meningoencephalitis. 12% of primary HSV 2 infections are apparent with sudden abortion, vulvovaginitis or penis scrotum efflorescences.
Detection and diagnosis
An important field of application for HSV serology - also during latency - is the detection of serotype-specific HSV IgG antibodies in order to identify potential HSV carriers who could infect susceptible individuals. In particular, the identification of HSV 2 serotype-specific antibodies in pregnant women, who present a high risk of transferring the virus to a newborn child, is recommended. The serological typing of an HSV infection is usually performed by identifying IgG antibodies directed against the viral surface glycoproteins G (gG) of HSV 1 (gG1) and HSV 2 (gG2). Due to the fact that these antibodies are only produced some weeks after a primary infection, the determination of serotype-specific antibodies can also assist in the differentiation between primary infection and reactivation

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
ESR1051G protocol

Documents

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