Herpes Simplex Virus 1 IgM Control Serum BC1051M

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Herpes Simplex Virus (HSV) 1 IgM Control Serum
Applications: ELISA
IgM control serum
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC1051M Categories: control serum, Virion/Serion kits Tags: ELISA control serum, Herpes simplex Virus, IgM

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Herpes Simplex Virus 1 reactive IgM
species reactivity	Herpes Simplex Virus
applications	ELISA
assay type	Indirect & quantitative
available size	3 mL

Herpes Simplex Virus 1 IgM Control Serum BC1051M

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Associated products Herpes simplex Virus 1 Glycoprotein G Antigen (BA1051RVS-G) Herpes simplex Virus 1 Antigen (BA1051VS) Herpes Simplex Virus 1 gP IgG Control Serum (BC1051G) Herpes Simplex Virus 1 IgM Control Serum (BC1051M) Herpes simplex Virus 1 IgG ELISA Kit (ESR1051G) Herpes simplex Virus 1 IgM ELISA Kit (ESR1051M)

target relevance

human antibody anti-Herpes Simplex Virus (HSV)

Herpes Simplex Virus (HSV)

Description
Virus that causes oral herpes, genital herpes, and other mucocutaneous infections

Structure
Herpes simplex viruses (HSV) are enveloped, double-stranded DNA viruses belonging to the genus Simplexvirus within the family Herpesviridae. Two closely related species, Herpes simplex virus type 1 (HSV-1) and Herpes simplex virus type 2 (HSV-2), are responsible for the majority of human infections. The viral genome is enclosed within an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing glycoproteins that mediate attachment and entry into host cells. Following primary infection, HSV establishes lifelong latency within sensory neurons, particularly in the trigeminal and sacral ganglia. Periodic reactivation of latent virus results in recurrent infections and viral shedding, often in the absence of symptoms. HSV infections are widespread globally and represent some of the most common viral infections of humans.

Diagnosis
The diagnosis of herpes simplex virus infection is performed through clinical evaluation and laboratory testing. Molecular methods such as polymerase chain reaction (PCR) are highly sensitive and specific and are considered the preferred diagnostic approach for detecting HSV DNA in lesion swabs, cerebrospinal fluid, and other clinical specimens. Viral culture may also be used, particularly for active lesions, although it is generally less sensitive than PCR. Direct fluorescent antibody testing and antigen detection assays may provide rapid identification in selected settings. Serological assays, including ELISA-based tests, can detect HSV-specific antibodies and help distinguish previous exposure to HSV-1 and HSV-2. Laboratory confirmation is particularly important in cases of neonatal herpes, encephalitis, and atypical presentations.

Symptoms
Herpes simplex virus infections produce a wide range of clinical manifestations depending on the site of infection and immune status of the host. Primary infection may be asymptomatic or may present with painful vesicular lesions involving the oral cavity, lips, genital region, skin, or eyes. HSV-1 most commonly causes oral herpes characterized by fever, gingivostomatitis, and recurrent cold sores, whereas HSV-2 is more frequently associated with genital herpes causing painful ulcers, itching, dysuria, and regional lymphadenopathy. Recurrent episodes are typically milder than primary infections due to partial immune control. In immunocompromised individuals and neonates, HSV can cause severe disseminated disease. Rare but serious complications include herpes encephalitis, keratitis leading to vision loss, meningitis, and neonatal herpes, which may be life-threatening if untreated.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application for the Herpes Simplex Virus 1 IgM Control Serum BC1051M?

The Herpes Simplex Virus 1 IgM Control Serum BC1051M is designed for use as a control serum in ELISA assays, specifically for the detection of HSV-1 reactive IgM antibodies using SERION ELISA classic and SERION ELISA antigen assays.

How should the Herpes Simplex Virus 1 IgM Control Serum BC1051M be stored to maintain stability?

This control serum should be stored at 2-8°C to ensure proper preservation and stability of the reactive IgM antibodies.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC1051M protocol

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Herpes Simplex Virus 1 IgM Control Serum BC1051M

Data

FAQ & Publications

Protocols

Documents

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