Herpes simplex Virus 1 Antigen BA1051VS

$819.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Herpes Simplex Virus (HSV) 1 Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA1051VS Category: Infectious disease proteins Tags: antigen, Herpes simplex Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Herpes simplex Virus 1
species reactivity	Herpes Simplex Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Herpes simplex Virus 1 Antigen BA1051VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Herpes simplex Virus 1 Glycoprotein G Antigen (BA1051RVS-G) Herpes simplex Virus 1 Antigen (BA1051VS) Herpes Simplex Virus 1 gP IgG Control Serum (BC1051G) Herpes Simplex Virus 1 IgM Control Serum (BC1051M) Herpes simplex Virus 1 IgG ELISA Kit (ESR1051G) Herpes simplex Virus 1 IgM ELISA Kit (ESR1051M)

target relevance
Herpes Simplex Virus (HSV)
Description Virus that causes oral herpes, genital herpes, and other mucocutaneous infections
Structure Herpes simplex viruses (HSV) are enveloped, double-stranded DNA viruses belonging to the genus Simplexvirus within the family Herpesviridae. Two closely related species, Herpes simplex virus type 1 (HSV-1) and Herpes simplex virus type 2 (HSV-2), are responsible for the majority of human infections. The viral genome is enclosed within an icosahedral capsid surrounded by a protein tegument and a lipid envelope containing glycoproteins that mediate attachment and entry into host cells. Following primary infection, HSV establishes lifelong latency within sensory neurons, particularly in the trigeminal and sacral ganglia. Periodic reactivation of latent virus results in recurrent infections and viral shedding, often in the absence of symptoms. HSV infections are widespread globally and represent some of the most common viral infections of humans.
Diagnosis The diagnosis of herpes simplex virus infection is performed through clinical evaluation and laboratory testing. Molecular methods such as polymerase chain reaction (PCR) are highly sensitive and specific and are considered the preferred diagnostic approach for detecting HSV DNA in lesion swabs, cerebrospinal fluid, and other clinical specimens. Viral culture may also be used, particularly for active lesions, although it is generally less sensitive than PCR. Direct fluorescent antibody testing and antigen detection assays may provide rapid identification in selected settings. Serological assays, including ELISA-based tests, can detect HSV-specific antibodies and help distinguish previous exposure to HSV-1 and HSV-2. Laboratory confirmation is particularly important in cases of neonatal herpes, encephalitis, and atypical presentations.
Symptoms Herpes simplex virus infections produce a wide range of clinical manifestations depending on the site of infection and immune status of the host. Primary infection may be asymptomatic or may present with painful vesicular lesions involving the oral cavity, lips, genital region, skin, or eyes. HSV-1 most commonly causes oral herpes characterized by fever, gingivostomatitis, and recurrent cold sores, whereas HSV-2 is more frequently associated with genital herpes causing painful ulcers, itching, dysuria, and regional lymphadenopathy. Recurrent episodes are typically milder than primary infections due to partial immune control. In immunocompromised individuals and neonates, HSV can cause severe disseminated disease. Rare but serious complications include herpes encephalitis, keratitis leading to vision loss, meningitis, and neonatal herpes, which may be life-threatening if untreated.

Data

FAQ & Publications

Frequently Asked Questions

What applications is the Herpes simplex Virus 1 Antigen BA1051VS suitable for?

The Herpes simplex Virus 1 Antigen BA1051VS is suitable for detecting IgA, IgG, and IgM antibodies in ELISA assays, specifically for indirect and quantitative assay types.

How should the Herpes simplex Virus 1 Antigen BA1051VS be stored to maintain its stability?

This antigen should be stored at -65°C or lower and should be protected from repeated freeze-thaw cycles. It is recommended to sonicate the product before use to ensure proper resuspension.

What species reactivity does the Herpes simplex Virus 1 Antigen BA1051VS exhibit?

The antigen is reactive with Herpes Simplex Virus species, specifically targeting Herpes simplex Virus 1.

What is the form and concentration information provided for the Herpes simplex Virus 1 Antigen BA1051VS?

The product is supplied in liquid form, and the lot-specific concentration is specified in mg/mL on the product label. The available size is 1 mg per vial.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.