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Chlamydia trachomatis IgM ELISA kit-SERION classic ESR1372M

$364.00

Summary

Virion/Serion Diagnostic Kit for research use (RUO)
Chlamydia trachomatis IgM ELISA Kit
Suitable for IgM detection
Ready-to-use
96 tests

SKU: ESR1372M Category: Virion/Serion kits Tags: Chlamydia, ELISA, IgM

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Chlamydia trachomatis reactive IgM
species reactivity	Chlamydia trachomatis
applications	ELISA
assay type	Indirect & quantitative
available sizes	96 tests

Chlamydia trachomatis IgM ELISA Kit ESR1372M

Assay type
Indirect ELISA

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Notes
Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results.

Components

Break apart microtiter test strips each with antigen coated single wells	8 x 12 (96 Total)
Standard serum (ready-to-use)	2 x 2 mL
Negative control serum (ready-to-use)	2 mL
Anti-human-IgM-conjugate (ready-to-use)	13 mL
Washing solution concentrate (sufficient for 1000ml)	33.3 mL
Dilution buffer	2 x 50 mL
Stopping solution	15 mL
Substrate (ready-to-use)	13 mL
Quality control certificate with standard curve and evaluation table	1

Storage
Store at 2-8°C.

Associated products
Chlamydia trachomatis EB + RB Antigen (BA1372VSER)
Chlamydia trachomatis MOMP Antigen (BA1372VSR2)
Chlamydia trachomatis IgA Control Serum (BC1372A)
Chlamydia trachomatis IgG Control Serum (BC1372G)
Chlamydia trachomatis IgM Control Serum (BC1372M)
Chlamydia trachomatis IgA ELISA Kit (ESR1372A)
Chlamydia trachomatis IgG ELISA Kit (ESR1372G)
Chlamydia trachomatis IgM ELISA Kit (ESR1372M)
Chlamydia IgA ELISA Kit (ESR137A)
Chlamydia IgG ELISA Kit (ESR137G)

target relevance

human antibody anti-Chlamydia trachomatis

Chlamydia trachomatis

Description
Bacterium that causes chlamydial sexually transmitted infections, trachoma, and lymphogranuloma venereum

Structure
Chlamydia trachomatis is an obligate intracellular Gram-negative bacterium belonging to the family Chlamydiaceae. The organism possesses a unique biphasic developmental cycle consisting of the infectious elementary body (EB) and the metabolically active reticulate body (RB). Elementary bodies are specialized for extracellular survival and host cell infection, while reticulate bodies replicate within membrane-bound intracellular inclusions inside host epithelial cells. Chlamydia trachomatis is a strictly human pathogen and is one of the most common bacterial causes of sexually transmitted infections worldwide. Different serovars are associated with distinct diseases, including urogenital infections, trachoma, and lymphogranuloma venereum (LGV). Because the organism relies extensively on host cellular machinery for replication, it cannot be propagated on conventional bacteriological culture media.

Diagnosis
The diagnosis of Chlamydia trachomatis infection is performed primarily through nucleic acid amplification tests (NAATs), including polymerase chain reaction (PCR)-based assays, which are considered the gold standard due to their high sensitivity and specificity. Testing can be performed using urine specimens, vaginal swabs, cervical swabs, urethral swabs, rectal swabs, or other appropriate clinical samples. Serological assays, including ELISA-based methods, may be useful for epidemiological studies or selected clinical situations but are generally less useful for diagnosing uncomplicated genital infections. Culture techniques are rarely used in routine clinical practice because of technical complexity. Early and accurate diagnosis is essential because many infections are asymptomatic and untreated disease can result in significant long-term complications.

Symptoms
Chlamydia trachomatis infection is frequently asymptomatic, particularly in women, which contributes to ongoing transmission. Symptomatic urogenital infection may present with dysuria, urethral discharge, cervicitis, abnormal vaginal discharge, pelvic pain, postcoital bleeding, or testicular pain. Untreated infection can ascend to cause pelvic inflammatory disease (PID), ectopic pregnancy, infertility, and chronic pelvic pain. Certain serovars cause lymphogranuloma venereum, characterized by genital ulcers followed by painful lymphadenopathy and proctocolitis. Ocular infection can result in trachoma, a chronic inflammatory eye disease that remains a leading infectious cause of blindness worldwide. Neonatal infection acquired during childbirth may cause conjunctivitis or pneumonia. Prompt diagnosis and treatment are important to prevent complications and reduce transmission.

Data

FAQ & Publications

Frequently Asked Questions

What type of samples can be used with the Chlamydia trachomatis IgM ELISA Kit ESR1372M?

The kit is suitable for use with serum, plasma, and whole blood samples for the detection of Chlamydia trachomatis reactive IgM antibodies.

How should the Chlamydia trachomatis IgM ELISA Kit ESR1372M be stored to maintain its stability?

The kit components should be stored at 2-8°C to ensure proper preservation and optimal assay performance.

Is there any recommended pretreatment to improve the accuracy of IgM detection with this ELISA kit?

Yes, pretreatment of samples with RF-Absorbent Z200 is recommended to remove IgM rheumatoid factors, which can cause false negative results and reduce signal specificity.

What is the assay type and format used in the ESR1372M kit for detecting Chlamydia trachomatis IgM antibodies?

The kit employs an indirect and quantitative ELISA assay format, utilizing antigen-coated microtiter wells for antibody detection.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ESR1372M protocol

Documents

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Chlamydia trachomatis IgM ELISA kit-SERION classic ESR1372M

RF-Absorbent Z200 for use with IgM ELISA kits

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

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