Parainfluenza Virus Type 1 Antigen BA1261VS

$855.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Parainfluenza Virus Type 1 Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA1261VS Category: Infectious disease proteins Tags: antigen, Parainfluenza Virus, protein

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Parainfluenza Virus Type 1
species reactivity	Parainfluenza Virus
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Parainfluenza Virus Type 1 Antigen BA1261VS

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Parainfluenza Virus Type 1 Antigen (BA1261VS) Parainfluenza Virus Type 2 Antigen (BA1262VS) Parainfluenza Virus Type 3 Control Antigen (BA1263VS) Parainfluenza Virus Human IgA Assay Control (BC126A) Parainfluenza Virus Human IgG Assay Control (BC126G) Parainfluenza Virus IgA ELISA Kit (ESR126A) Parainfluenza Virus IgG ELISA Kit (ESR126G)

target relevance
Parainfluenza Virus
Description Virus that causes upper and lower respiratory tract infections, including croup
Structure Human parainfluenza viruses (HPIVs) are enveloped, negative-sense, single-stranded RNA viruses belonging to the family Paramyxoviridae. Four major types, HPIV-1, HPIV-2, HPIV-3, and HPIV-4, are recognized as important human respiratory pathogens. The viral envelope contains hemagglutinin-neuraminidase (HN) and fusion (F) glycoproteins that facilitate attachment to and entry into host respiratory epithelial cells. Human parainfluenza viruses are distributed worldwide and are among the most common causes of respiratory tract infections in infants and young children, although reinfections frequently occur throughout life. HPIV-1 and HPIV-2 are particularly associated with croup, while HPIV-3 is a major cause of bronchiolitis and pneumonia. The viruses are transmitted through respiratory droplets, direct contact with respiratory secretions, and contaminated surfaces.
Diagnosis The diagnosis of parainfluenza virus infection is performed through molecular, antigen detection, and serological methods. Reverse transcription polymerase chain reaction (RT-PCR) is the preferred diagnostic method due to its high sensitivity and specificity and is commonly included in multiplex respiratory pathogen panels. Viral RNA can be detected in nasopharyngeal swabs, throat swabs, and other respiratory specimens. Antigen detection assays and direct immunofluorescence tests may provide more rapid results but generally have lower sensitivity than molecular methods. Viral culture may be used in specialized laboratories, while serological assays are primarily utilized for epidemiological studies and research purposes. Laboratory confirmation is particularly useful in hospitalized patients, immunocompromised individuals, and outbreak investigations.
Symptoms Parainfluenza virus infections typically develop following an incubation period of approximately two to seven days. Clinical manifestations vary according to patient age, immune status, and viral type. Common symptoms include fever, runny nose, nasal congestion, sore throat, cough, hoarseness, and malaise. In young children, parainfluenza viruses are a leading cause of croup, characterized by a distinctive barking cough, inspiratory stridor, and respiratory distress due to inflammation of the upper airway. Lower respiratory tract involvement may result in bronchiolitis, bronchitis, or pneumonia, particularly in infants, elderly individuals, and immunocompromised patients. While most infections are self-limiting, severe respiratory disease may occur in vulnerable populations and occasionally requires hospitalization.

Data

FAQ & Publications

Frequently Asked Questions

What is the recommended storage condition for the Parainfluenza Virus Type 1 Antigen BA1261VS?

The antigen should be stored at -65°C or lower and repeated freeze-thaw cycles should be avoided. Under these conditions, it is stable for up to 10 years from the date of manufacture.

For which immunoglobulin classes is the Parainfluenza Virus Type 1 Antigen suitable for detection in ELISA assays?

This antigen is suitable for the detection of IgA, IgG, and IgM antibodies in ELISA applications.

What is the species reactivity of the Parainfluenza Virus Type 1 Antigen BA1261VS?

The antigen is reactive with Parainfluenza Virus species, specifically targeting Parainfluenza Virus Type 1.

What is the recommended assay format when using Parainfluenza Virus Type 1 Antigen BA1261VS in ELISA?

The antigen is designed for use in indirect and quantitative ELISA assays for antibody detection.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.