rabbit anti-MDA (malondialdehyde) polyclonal antibody 1027

Price range: $100.00 through $2,600.00

Antibody summary

Rabbit polyclonal to Malondialdehyde (MDA)
Suitable for: WB, ELISA
Reacts with: MDA modified protein
Isotype: IgG
1 mg, 100 µg, 25 µg

available sizes

Clear

SKU: 1027parent Categories: antibody, oxidative stress Tag: MDA

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	rabbit
isotype	IgG
clonality	polyclonal
concentration	1 mg/mL
applications	ELISA, WB
reactivity	all
available sizes	1 mg, 100 µg, 25 µg

rabbit anti- mda polyclonal antibody 1027

antibody

Tested applications WB, ELISA
Recommended dilutions Enzyme-Linked Immunosorbent Assay (ELISA) 1:1000 - 1:20,000, Western Blot (WB) 1:1000 - 1:20,000
Immunogen MDA-KLH
Size and concentration 25, 100, 1000µL and 1 mg/mL
Form liquid
Storage Instructions Store at 2-8°C. Expires 1 year from date of receipt.
Storage buffer 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.2
Purity affinity purified
Clonality polyclonal
Isotype IgG
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control Rabbit polyclonal - Isotype Control

target relevance
MDA
Protein names Malondialdehyde
Alternative names MDA, Malonic dialdehyde, Propanedial
Function MDA is a reactive end-product of lipid peroxidation and can form covalent adducts with proteins, lipids, and nucleic acids.
Post-translational modification MDA reacts with lysine, histidine, arginine, and other nucleophilic residues to form stable MDA-protein adducts. These modified molecules are often immunogenic and are recognized by anti-MDA antibodies.
Involvement in disease Elevated MDA levels have been associated with cardiovascular disease, atherosclerosis, diabetes, neurodegenerative disorders, chronic inflammation, cancer, and aging.
Description Malondialdehyde (MDA) is a highly reactive aldehyde generated during lipid peroxidation of polyunsaturated fatty acids. It is one of the most widely used biomarkers of oxidative stress and lipid oxidation.
Chemical description Reactive aldehyde C3H4O2 72.06 Da
Related entities relationship: forms_adduct_with; entity: Low-density lipoprotein relationship: forms_adduct_with; entity: Albumin relationship: forms_adduct_with; entity: Proteins relationship: derived_from; entity: Lipid peroxidation relationship: related_to; entity: 4-Hydroxynonenal relationship: related_to; entity: Oxidized LDL relationship: related_to; entity: MDA-LDL
Keywords Reactive aldehyde, Lipid peroxidation, Oxidative stress, Oxidative damage, Biomarker
Structure Malondialdehyde is a small reactive dialdehyde (propanedial) generated during oxidative degradation of polyunsaturated lipids.
Formation MDA is produced as a terminal product of lipid peroxidation during oxidative stress and inflammatory processes.
Protein modification MDA readily reacts with amino groups on proteins to form MDA-protein adducts, which can alter protein function and generate neoepitopes recognized by the immune system.
Clinical relevance Elevated MDA concentrations are associated with oxidative stress, cardiovascular disease, diabetes, neurodegeneration, chronic inflammation, and cancer.
Research relevance MDA is widely used as a biomarker of lipid peroxidation and oxidative damage and is frequently measured by ELISA, TBARS assays, HPLC, and mass spectrometry.

Data

No results found

FAQ & Publications

Frequently Asked Questions

What applications is the rabbit anti-MDA polyclonal antibody 1027 validated for?

This antibody is validated for use in Western Blot (WB) and Enzyme-Linked Immunosorbent Assay (ELISA).

How should the rabbit anti-MDA polyclonal antibody 1027 be stored to maintain stability?

Store the antibody at 2-8°C and it is stable for 1 year from the date of receipt.

What is the host species and clonality of the anti-MDA antibody 1027?

The antibody is a rabbit-derived polyclonal antibody with an IgG isotype.

What is the recommended dilution range for using this antibody in ELISA and Western Blot?

Recommended dilutions are between 1:1000 to 1:20,000 for both ELISA and Western Blot applications.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.