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rabbit anti-STAT6 (phospho-Tyr641) polyclonal antibody 6192

$366.00

Antibody summary

  • Rabbit polyclonal to STAT6 (phospho-Tyr641)
  • Suitable for: WB,IHC
  • Isotype: Whole IgG
  • 100 µl
SKU: 6192parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

STAT6 (phospho-Tyr641)

available sizes

100 µL

Available product – rabbit anti-STAT6 (phospho-Tyr641) polyclonal antibody 6192

antibody
Tested applications
WB,IHC,IHC
Recommended dilutions
Immunoblotting: use at dilution of 1:500-1:1,000. A band of~110kDa is detected.

Immunohistochemistry: use at dilution of 1:50- 1:100.

These are recommended working dilutions.

End user should determine optimal dilutions for their applications.
Immunogen
Peptide sequence that includes phosphorylation site of tyrosine 641 (R-G-Y(p)-V-P) derived from human STAT6 and conjugated to KLH.
Size and concentration
100µL and 1 mg/mL
Form
liquid
Storage Instructions
This antibody is stable for at least one (1) year at -20°C.
Storage buffer
PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl,
Purity
affinity purified
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Signal transducer and activator of transcription 6 (IL-4 Stat)
Gene names
STAT6,STAT6
Protein family
Transcription factor STAT family
Mass
94135Da
Function
FUNCTION: Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. {ECO:0000269|PubMed:17210636}.
Subellular location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Structure
SUBUNIT: Forms a homodimer or a heterodimer with a related family member (By similarity). Interacts with NCOA1 via its C-terminal LXXLL motif. {ECO:0000250, ECO:0000269|PubMed:12138096, ECO:0000269|PubMed:14757047}.
Post-translational modification
PTM: Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4 (PubMed:27796300). Tyrosine phosphorylated following stimulation by IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling (PubMed:17210636). {ECO:0000250|UniProtKB:P52633, ECO:0000269|PubMed:17210636, ECO:0000269|PubMed:27796300}.; PTM: Mono-ADP-ribosylated by PARP14. {ECO:0000269|PubMed:27796300}.
Target Relevance information above includes information from UniProt accession : P42226
The UniProt Consortium

Data

No results found

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC

Documents

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No results found

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