| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Neurturin |
| available sizes | 100 µg |
rabbit anti-Neurturin polyclonal antibody 6199
$445.00
Antibody summary
- Rabbit polyclonal to Neurturin
- Suitable for: ELISA,WB,IHC-P,IF
- Isotype: IgG
- 100 µg
rabbit anti-Neurturin polyclonal antibody 6199
| target relevance |
|---|
| Protein names Neurturin |
| Gene names NRTN,NRTN |
| Protein family TGF-beta family, GDNF subfamily |
| Mass 22405Da |
| Function Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. |
| Subellular location Secreted. |
| Structure Homodimer; disulfide-linked. |
| Involvement in disease DISEASE: Note=Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. |
| Target Relevance information above includes information from UniProt accession: Q99748 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of NTN in HeLa cell lyaste containing 10 or 2.5 ng of full length recombinant NTN with neurturin antibody at 1:500. |
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| Immunohistochemistry of neurturin in human brain tissue with neurturin antibody at 5 µg/mL. |
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| Immunofluorescence of Neurturin in human brain tissue with Neurturin antibody at 5 µg/mL.
Green: Neuriturin Antibody (6199) Red: Phylloidin staining Blue: DAPI staining |
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| Immunohistochemistry of Neurturin in human brain tissue with Neurturin antibody at 5 µg/mL. |
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| Immunohistochemistry of Neurturin in mouse brain tissue with Neurturin Antibody at 5 µg/mL. |
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| Immunofluorescence of Neurturin in mouse brain tissue with Neurturin Antibody at 20 µg/mL.
Green: Neuriturin Antibody (6199) Red: Phylloidin staining Blue: DAPI staining |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| Western blot IHC ICC |
Documents
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| Please enter your product and batch number here to retrieve - product datasheet, SDS, and QC information. | |||
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