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rabbit anti-Neurturin polyclonal antibody 6199

$445.00

Antibody summary

  • Rabbit polyclonal to Neurturin
  • Suitable for: ELISA,WB,IHC-P,IF
  • Isotype: IgG
  • 100 µg
SKU: 6199parent Category: Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

Neurturin

available sizes

100 µg

rabbit anti-Neurturin polyclonal antibody 6199

antibody
Tested applications
WB,IHC,IHC,ICC/IF,ELISA
Recommended dilutions
Immunoblotting: use at 1:500 dilution.
Immunogen
Peptide corresponding to aa 178-193 of human neurturin.
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Storage buffer
PBS, pH 7.4.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Neurturin
Gene names
NRTN,NRTN
Protein family
TGF-beta family, GDNF subfamily
Mass
22405Da
Function
Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Subellular location
Secreted.
Structure
Homodimer; disulfide-linked.
Involvement in disease
DISEASE: Note=Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
Target Relevance information above includes information from UniProt accession: Q99748
The UniProt Consortium

Data

benchmark-antibodies_anti-neurturin_antibody_6199_1.jpg
Western blot analysis of NTN in HeLa cell lyaste containing 10 or 2.5 ng of full length recombinant NTN with neurturin antibody at 1:500.
benchmark-antibodies_anti-neurturin_antibody_6199_2.jpg
Immunohistochemistry of neurturin in human brain tissue with neurturin antibody at 5 µg/mL.
benchmark-antibodies_anti-neurturin_antibody_6199_3.gif
Immunofluorescence of Neurturin in human brain tissue with Neurturin antibody at 5 µg/mL. Green: Neuriturin Antibody (6199)
Red: Phylloidin staining
Blue: DAPI staining
benchmark-antibodies_anti-neurturin_antibody_6199_4.gif
Immunohistochemistry of Neurturin in human brain tissue with Neurturin antibody at 5 µg/mL.
benchmark-antibodies_anti-neurturin_antibody_6199_5.gif
Immunohistochemistry of Neurturin in mouse brain tissue with Neurturin Antibody at 5 µg/mL.
benchmark-antibodies_anti-neurturin_antibody_6199_6.gif
Immunofluorescence of Neurturin in mouse brain tissue with Neurturin Antibody at 20 µg/mL. Green: Neuriturin Antibody (6199)
Red: Phylloidin staining
Blue: DAPI staining

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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