| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | MUC12 |
| available sizes | 100 µg |
rabbit anti-MUC12 polyclonal antibody 4071
$376.00
Antibody summary
- Rabbit polyclonal to MUC12
- Suitable for: WB
- Isotype: Whole IgG
- 100 µg
rabbit anti-MUC12 polyclonal antibody 4071
| target relevance |
|---|
| Protein names Mucin-12 (MUC-12) (Mucin-11) (MUC-11) |
| Gene names MUC12,MUC12 MUC11 |
| Mass 558164Da |
| Function FUNCTION: Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. {ECO:0000269|PubMed:17058067}. |
| Subellular location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissues TISSUE SPECIFICITY: Ubiquitous, with higher expression in colon. Down-regulated in colorectal cancer as well as in the colon of patients with ulcerative colitis (UC) and Crohn's disease (CD). {ECO:0000269|PubMed:10463611, ECO:0000269|PubMed:17058067}. |
| Domain DOMAIN: The proteolytic cleavage occurs within the SEA domain. This domain is not interchangeable, suggesting that it is insufficient to mediate efficient cleavage. {ECO:0000269|PubMed:15943821}. |
| Target Relevance information above includes information from UniProt accession: Q9UKN1 |
| The UniProt Consortium |
Data
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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