| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | MUC12 |
| available sizes | 100 µg |
rabbit anti-MUC12 polyclonal antibody 1354
$376.00
Antibody summary
- Rabbit polyclonal to MUC12
- Suitable for: WB
- Isotype: Whole IgG
- 100 µg
rabbit anti-MUC12 polyclonal antibody 1354
| target relevance |
|---|
| Protein names Mucin-12 (MUC-12) (Mucin-11) (MUC-11) |
| Gene names MUC12,MUC12 MUC11 |
| Mass 558164Da |
| Function FUNCTION: Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. {ECO:0000269|PubMed:17058067}. |
| Subellular location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissues TISSUE SPECIFICITY: Ubiquitous, with higher expression in colon. Down-regulated in colorectal cancer as well as in the colon of patients with ulcerative colitis (UC) and Crohn's disease (CD). {ECO:0000269|PubMed:10463611, ECO:0000269|PubMed:17058067}. |
| Domain DOMAIN: The proteolytic cleavage occurs within the SEA domain. This domain is not interchangeable, suggesting that it is insufficient to mediate efficient cleavage. {ECO:0000269|PubMed:15943821}. |
| Target Relevance information above includes information from UniProt accession: Q9UKN1 |
| The UniProt Consortium |
Data
| No results found |
FAQ & Publications
Frequently Asked Questions
What species was the anti-MUC12 polyclonal antibody raised in?
This anti-MUC12 polyclonal antibody was raised in rabbit.
Which applications has the rabbit anti-MUC12 polyclonal antibody 1354 been validated for?
The antibody has been tested and is suitable for Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF) applications.
What is the recommended dilution range for using this antibody in immunoblotting?
For immunoblotting, it is recommended to use the antibody at a dilution between 1:500 and 1:1,000.
How should the rabbit anti-MUC12 antibody be stored to maintain stability?
This antibody should be stored at -20°C and is stable for at least one year. It is advised to avoid multiple freeze-thaw cycles to preserve antibody integrity.
What is the immunogen used to generate the rabbit anti-MUC12 polyclonal antibody 1354?
The immunogen is a peptide corresponding to amino acids 10-24 of human Mucin 12.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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