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rabbit anti-MTBP polyclonal antibody 9173

$445.00

Antibody summary

  • Rabbit polyclonal to MTBP
  • Suitable for: ELISA,WB,ICC,IF
  • Isotype: Whole IgG
  • 100 µg
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SKU: 9173parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

MTBP

available sizes

100 µg

antibody
Tested applications
WB,ICC/IF,ELISA
Recommended dilutions
Immunoblotting: use at 0.5-1 ug/mL. In immunoblots, a band of 104 kD is detected.

Positive control: K562 cell lysate.
Immunogen
Peptide corresponding to aa 122-139 of human MTBP. This sequence differs from that of mouse by three amino acids.
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Storage buffer
PBS, pH 7.4.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Mdm2-binding protein (hMTBP)
Gene names
MTBP,MTBP
Protein family
MTBP family
Mass
102193Da
Function
FUNCTION: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. {ECO:0000250, ECO:0000269|PubMed:15632057}.
Structure
SUBUNIT: Interacts with MDM2. {ECO:0000269|PubMed:15632057}.
Target Relevance information above includes information from UniProt accession : Q96DY7
The UniProt Consortium

Data

benchmark-antibodies_anti-mtbp_antibody_9173_1.gif
Western blot analysis of MTBP expression in K562 cell lysate with MTBP antibody at (A) 1 and (B) 2 µg/mL.
benchmark-antibodies_anti-mtbp_antibody_9173_2.jpg
Immunocytochemistry of MTBP in K562 cells with MTBP antibody at 5 µg/mL.
benchmark-antibodies_anti-mtbp_antibody_9173_3.jpg
Immunofluorescence of MTBP in K562 cells with MTBP antibody at 20 µg/mL.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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