| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | MTBP |
| available sizes | 100 µg |
rabbit anti-MTBP polyclonal antibody 9173
$445.00
Antibody summary
- Rabbit polyclonal to MTBP
- Suitable for: ELISA,WB,ICC,IF
- Isotype: Whole IgG
- 100 µg
rabbit anti-MTBP polyclonal antibody 9173
| antibody |
|---|
| Tested applications WB,ICC/IF,ELISA |
| Recommended dilutions Immunoblotting: use at 0.5-1 ug/mL. In immunoblots, a band of 104 kD is detected. Positive control: K562 cell lysate. |
| Immunogen Peptide corresponding to aa 122-139 of human MTBP. This sequence differs from that of mouse by three amino acids. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinty purifcation |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Mdm2-binding protein (hMTBP) |
| Gene names MTBP,MTBP |
| Protein family MTBP family |
| Mass 102193Da |
| Function FUNCTION: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. {ECO:0000250, ECO:0000269|PubMed:15632057}. |
| Structure SUBUNIT: Interacts with MDM2. {ECO:0000269|PubMed:15632057}. |
| Target Relevance information above includes information from UniProt accession : Q96DY7 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of MTBP expression in K562 cell lysate with MTBP antibody at (A) 1 and (B) 2 µg/mL. |
 |
| Immunocytochemistry of MTBP in K562 cells with MTBP antibody at 5 µg/mL. |
 |
| Immunofluorescence of MTBP in K562 cells with MTBP antibody at 20 µg/mL. |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
|---|
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
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| No results found | |||
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