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rabbit anti-IL-21R (ED) polyclonal antibody 6790

$445.00

Antibody summary

  • Rabbit polyclonal to IL-21R (ED)
  • Suitable for: ELISA,WB,IHC-P,IF
  • Isotype: Whole IgG
  • 100 µg
SKU: 6790parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

Interleukin-21 Receptor (IL-21R) (ED)

available sizes

100 µg

Available product – rabbit anti-IL-21R (ED) polyclonal antibody 6790

antibody
Tested applications
WB,IHC,IHC,ICC/IF,ELISA
Recommended dilutions
Immunoblotting: use at 0.5-1 ug/mL. In immunoblots, a band of 60 kD is detected.

Positive control: Raji cell lysate.
Immunogen
Peptide corresponding to aa 97-111 of human IL-21R precursor.
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Storage buffer
PBS, pH 7.4.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Interleukin-21 receptor (IL-21 receptor) (IL-21R) (Novel interleukin receptor) (CD antigen CD360)
Gene names
IL21R,IL21R NILR UNQ3121/PRO10273
Protein family
Type I cytokine receptor family, Type 4 subfamily
Mass
59130Da
Function
FUNCTION: This is a receptor for interleukin-21.
Subellular location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Tissues
TISSUE SPECIFICITY: Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.
Structure
SUBUNIT: Heterodimer with the common gamma subunit. Associates with JAK1. {ECO:0000269|PubMed:22235133}.
Post-translational modification
PTM: C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame.
Domain
TOPO_DOM 2
Target Relevance information above includes information from UniProt accession : Q9HBE5
The UniProt Consortium

Data

benchmark-antibodies_anti-interleukin-21_receptor_il-21r_ed_antibody_67
Western blot analysis of IL-21 receptor expression in human HepG2 cell lysate with IL-21 receptor antibody at (A) 1 and (B) 2 µg/mL.
benchmark-antibodies_anti-interleukin-21_receptor_il-21r_ed_antibody_67
Immunohistochemistry of IL-21 receptor in rat lung with IL-21 receptor antibody at 10 µg/mL.
benchmark-antibodies_anti-interleukin-21_receptor_il-21r_ed_antibody_67
Immunofluorescence of IL-21 Receptor in Rat Lung cells with IL-21 Receptor antibody at 20 µg/mL.
benchmark-antibodies_anti-interleukin-21_receptor_il-21r_ed_antibody_67
Immunofluorescence of IL21R in A431 cells with IL 21 Receptor antibody at 20 µg/mL. Green: IL-21 Receptor Antibody (6790)
Blue: DAPI staining

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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