| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Interleukin-21 Receptor (IL-21R) (ED) |
| available sizes | 100 µg |
rabbit anti-IL-21R (ED) polyclonal antibody 6790
$445.00
Antibody summary
- Rabbit polyclonal to IL-21R (ED)
- Suitable for: ELISA,WB,IHC-P,IF
- Isotype: Whole IgG
- 100 µg
rabbit anti-IL-21R (ED) polyclonal antibody 6790
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions Immunoblotting: use at 0.5-1 ug/mL. In immunoblots, a band of 60 kD is detected. Positive control: Raji cell lysate. |
| Immunogen Peptide corresponding to aa 97-111 of human IL-21R precursor. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinty purifcation |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Interleukin-21 receptor (IL-21 receptor) (IL-21R) (Novel interleukin receptor) (CD antigen CD360) |
| Gene names IL21R,IL21R NILR UNQ3121/PRO10273 |
| Protein family Type I cytokine receptor family, Type 4 subfamily |
| Mass 59130Da |
| Function FUNCTION: This is a receptor for interleukin-21. |
| Subellular location SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| Tissues TISSUE SPECIFICITY: Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen. |
| Structure SUBUNIT: Heterodimer with the common gamma subunit. Associates with JAK1. {ECO:0000269|PubMed:22235133}. |
| Post-translational modification PTM: C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame. |
| Domain TOPO_DOM 2 |
| Target Relevance information above includes information from UniProt accession : Q9HBE5 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of IL-21 receptor expression in human HepG2 cell lysate with IL-21 receptor antibody at (A) 1 and (B) 2 µg/mL. |
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| Immunohistochemistry of IL-21 receptor in rat lung with IL-21 receptor antibody at 10 µg/mL. |
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| Immunofluorescence of IL-21 Receptor in Rat Lung cells with IL-21 Receptor antibody at 20 µg/mL. |
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| Immunofluorescence of IL21R in A431 cells with IL 21 Receptor antibody at 20 µg/mL.
Green: IL-21 Receptor Antibody (6790) Blue: DAPI staining |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| Western blot IHC ICC |
Documents
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