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rabbit anti-DRAK1 (NT) polyclonal antibody 2814

$445.00

Antibody summary

  • Rabbit polyclonal to DRAK1 (NT)
  • Suitable for: ELISA,WB,ICC,IF
  • Isotype: IgG
  • 100 µg
SKU: 2814parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

DRAK1 (NT)

available sizes

100 µg

Available product – rabbit anti-DRAK1 (NT) polyclonal antibody 2814

antibody
Tested applications
WB,ICC/IF,ELISA
Recommended dilutions
Immunoblotting : use at 1ug/mL.

Immunocytochemistry: use at 2ug/mL.

Positive control: Whole cell lysate from A431 or MOLT4 cells.

These are recommended concentrations.

Enduser should determine optimal concentrations for their applications.
Immunogen
Peptide corresponding to aa 5-19 of human DRAK1 (accession no. Q9UEE5).
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Storage buffer
PBS, pH 7.4.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1)
Gene names
STK17A,STK17A DRAK1
Protein family
Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamil
Mass
46558Da
Function
FUNCTION: Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species. {ECO:0000269|PubMed:21489989, ECO:0000269|PubMed:9786912}.
Catalytic activity
CATALYTIC ACTIVITY: Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; CATALYTIC ACTIVITY: Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1;
Subellular location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9786912}.
Tissues
TISSUE SPECIFICITY: Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9786912}.
Post-translational modification
PTM: Autophosphorylated.
Target Relevance information above includes information from UniProt accession : Q9UEE5
The UniProt Consortium

Data

benchmark-antibodies_anti-drak1_nt_antibody_2814_1.jpg
Western blot analysis of DRAK1 in (A) MOLT4 and (B) A431 whole cell lysates with DRAK1 antibody at 1 µg/mL.
benchmark-antibodies_anti-drak1_nt_antibody_2814_2.jpg
Immunocytochemistry staining of MOLT4 cells using DRAK1 antibody at 2 µg/mL.
benchmark-antibodies_anti-drak1_nt_antibody_2814_3.jpg
Immunofluorescence of DRAK1 in Molt cells with DRAK1 antibody at 20 µg/mL.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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