| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | DENTT |
| available sizes | 100 µg |
rabbit anti-DENTT polyclonal antibody 2092
$376.00
Antibody summary
- Rabbit polyclonal to DENTT
- Suitable for: WB
- Isotype: Whole IgG
- 100 µg
rabbit anti-DENTT polyclonal antibody 2092
| target relevance |
|---|
| Protein names Testis-specific Y-encoded-like protein 2 (TSPY-like protein 2) (Cell division autoantigen 1) (Cutaneous T-cell lymphoma-associated antigen se20-4) (CTCL-associated antigen se20-4) (Differentially-expressed nucleolar TGF-beta1 target protein) (Nuclear protein of 79 kDa) (NP79) |
| Gene names TSPYL2,TSPYL2 CDA1 DENTT TSPX HRIHFB2216 |
| Protein family Nucleosome assembly protein (NAP) family |
| Mass 79435Da |
| Function FUNCTION: Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. {ECO:0000269|PubMed:11395479, ECO:0000269|PubMed:17317670}. |
| Subellular location SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11318608, ECO:0000269|PubMed:11395479}. Cytoplasm {ECO:0000250}. Note=Enriched in transcriptionally active regions of chromatin in neurons. {ECO:0000250}. |
| Tissues TISSUE SPECIFICITY: Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. {ECO:0000269|PubMed:11149944, ECO:0000269|PubMed:11318608, ECO:0000269|PubMed:12393179, ECO:0000269|PubMed:15241014}. |
| Structure SUBUNIT: Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TBR1 and TSPYL2 (By similarity). {ECO:0000250}. |
| Post-translational modification PTM: Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. {ECO:0000305|PubMed:11395479}. |
| Target Relevance information above includes information from UniProt accession : Q9H2G4 |
| The UniProt Consortium |
Data
| No results found |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| Western blot IHC ICC |
Documents
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