| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | DENTT |
| available sizes | 100 µg |
rabbit anti-DENTT polyclonal antibody 2092
$376.00
Antibody summary
- Rabbit polyclonal to DENTT
- Suitable for: WB
- Isotype: Whole IgG
- 100 µg
rabbit anti-DENTT polyclonal antibody 2092
| target relevance |
|---|
| Protein names Testis-specific Y-encoded-like protein 2 (TSPY-like protein 2) (Cell division autoantigen 1) (Cutaneous T-cell lymphoma-associated antigen se20-4) (CTCL-associated antigen se20-4) (Differentially-expressed nucleolar TGF-beta1 target protein) (Nuclear protein of 79 kDa) (NP79) |
| Gene names TSPYL2,TSPYL2 CDA1 DENTT TSPX HRIHFB2216 |
| Protein family Nucleosome assembly protein (NAP) family |
| Mass 79435Da |
| Function FUNCTION: Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. {ECO:0000269|PubMed:11395479, ECO:0000269|PubMed:17317670}. |
| Subellular location SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11318608, ECO:0000269|PubMed:11395479}. Cytoplasm {ECO:0000250}. Note=Enriched in transcriptionally active regions of chromatin in neurons. {ECO:0000250}. |
| Tissues TISSUE SPECIFICITY: Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. {ECO:0000269|PubMed:11149944, ECO:0000269|PubMed:11318608, ECO:0000269|PubMed:12393179, ECO:0000269|PubMed:15241014}. |
| Structure SUBUNIT: Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TBR1 and TSPYL2 (By similarity). {ECO:0000250}. |
| Post-translational modification PTM: Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. {ECO:0000305|PubMed:11395479}. |
| Target Relevance information above includes information from UniProt accession: Q9H2G4 |
| The UniProt Consortium |
Data
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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