| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | DC-SIGN (CT) |
| available sizes | 100 µg |
rabbit anti-DC-SIGN (CT) polyclonal antibody 1240
$469.00
Antibody summary
- Rabbit polyclonal to DC-SIGN (CT)
- Suitable for: ELISA,WB,IHC-P,IF
- Isotype: Whole IgG
- 100 µg
rabbit anti-DC-SIGN (CT) polyclonal antibody 1240
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions Immunoblotting: use at 1-2 ug/mL. In immunoblots, a band of 44 kD is detected. Positive control: Human placenta tissue lysate. |
| Immunogen Peptide corresponding to aa 384-404 of human DC-SIGN. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Homo sapiens CD209 CD209 antigen |
| Protein names CD209 antigen |
| Alternative names C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1 |
| Gene names CD209 |
| Function Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response |
| Subcellular location Secreted |
| Structure (Microbial infection) Interacts with whole M.bovis cells in a Ca(2+)-dependent and independent manner; in vitro experiments suggest it interacts with CH60.1 (groL1), DnaK, GADPH (gap) and LrpG (PubMed:21203928) |
| Keywords 3D-structure, Adaptive immunity, Alternative splicing, Calcium, Cell adhesion, Cell membrane, Disulfide bond, Endocytosis, Glycoprotein, Host cell receptor for virus entry, Host-virus interaction, Immunity, Innate immunity, Lectin, Mannose-binding, Membrane, Metal-binding, Proteomics identification, Receptor, Reference proteome, Repeat, Secreted, Signal-anchor, Transmembrane, Transmembrane helix |
| Sequence MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQV SKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKL QEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAV GELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQ ELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQ NFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFS GNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA |
| UniProt accession: Q9NNX6 |
Data
 |
| Western blot detection of DC-SIGN in human small intestine at (A) 1 and (B) 2 µg/mL. |
 |
| Immunohistochemistry of DC-SIGN in human lymph node tissue with DC-SIGN antibody at 10 µg/mL. |
 |
| Immunofluorescence of DC-SIGN in Human Lymph Node tissue with DC-SIGN antibody at 20 µg/mL. |
FAQ & Publications
Frequently Asked Questions
What applications has the rabbit anti-DC-SIGN (CT) polyclonal antibody 1240 been validated for?
This antibody has been tested and is suitable for use in Western blotting (WB), immunohistochemistry on paraffin-embedded sections (IHC-P), immunofluorescence (IF), immunocytochemistry (ICC), and ELISA applications.
How should the rabbit anti-DC-SIGN (CT) polyclonal antibody 1240 be stored to maintain stability?
The antibody should be stored at -20°C and is stable for at least one year under these conditions. It is recommended to avoid multiple freeze-thaw cycles to preserve antibody integrity.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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