| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Cyclin E2 |
| available sizes | 100 µg |
rabbit anti-Cyclin E2 polyclonal antibody 3718
$376.00
Antibody summary
- Rabbit polyclonal to Cyclin E2
- Suitable for: ELISA
- Isotype: Whole IgG
- 100 µg
rabbit anti-Cyclin E2 polyclonal antibody 3718
| target relevance |
|---|
| Protein names G1/S-specific cyclin-E2 |
| Gene names CCNE2,CCNE2 |
| Protein family Cyclin family, Cyclin E subfamily |
| Mass 46757Da |
| Function FUNCTION: Essential for the control of the cell cycle at the late G1 and early S phase. {ECO:0000269|PubMed:9840927, ECO:0000269|PubMed:9840943, ECO:0000269|PubMed:9858585}. |
| Subellular location SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9840943}. |
| Tissues TISSUE SPECIFICITY: According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor-derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon. {ECO:0000269|PubMed:9840927, ECO:0000269|PubMed:9840943, ECO:0000269|PubMed:9858585}. |
| Structure SUBUNIT: Interacts with the CDK2 (in vivo) and CDK3 (in vitro) protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. {ECO:0000269|PubMed:9840943}. |
| Post-translational modification PTM: Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway. {ECO:0000269|PubMed:9858585}.; PTM: Lactylated at Lys-348 (PubMed:36896611). Delactylated by SIRT3 (PubMed:36896611). {ECO:0000269|PubMed:36896611}. |
| Target Relevance information above includes information from UniProt accession: O96020 |
| The UniProt Consortium |
Data
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| ELISA |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.