| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Caspase-13 |
| available sizes | 100 µg |
rabbit anti-Caspase-13 polyclonal antibody 3345
$445.00
Antibody summary
- Rabbit polyclonal to Caspase-13
- Suitable for: ELISA,WB,IHC-P
- Isotype: IgG
- 100 µg
rabbit anti-Caspase-13 polyclonal antibody 3345
| antibody |
|---|
| Tested applications WB,IHC,IHC,ELISA |
| Recommended dilutions Immunoblotting: use at 1ug/mL. Immunohistochemistry: use at 10ug/mL. These are recommended concentrations. Endusers should determine optimal concentrations for their applications. Positive control: Whole cell lysate from HL60 cells. |
| Immunogen Peptide corresponding to aa 91- 105 of human caspase-13 (accession no. O75601). |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Caspase-13 (CASP-13) (EC 3.4.22.-) (Evolutionary related interleukin-1-beta-converting enzyme) (ERICE) [Cleaved into: Caspase-13 subunit 1; Caspase-13 subunit 2] |
| Gene names CASP13,CASP13 |
| Protein family Peptidase C14A family |
| Mass 43012Da |
| Function FUNCTION: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. |
| Tissues TISSUE SPECIFICITY: Mainly expressed in peripheral blood lymphocytes, spleen and placenta. |
| Structure SUBUNIT: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a small and a large subunit. {ECO:0000250}. |
| Post-translational modification PTM: The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. |
| Target Relevance information above includes information from UniProt accession: O75601 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of caspase-13 in human HL60 cell lysate (A), mouse brain (B) and rat brain (C) tissue lysates with caspase-13 antibody at 1 µg/mL. |
 |
| Immunohistochemistry of caspase-13 in mouse brain tissue with caspase-13 antibody at 10 µg/mL. |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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