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rabbit anti-Caspase-12 (NT) polyclonal antibody 8362

$445.00

Antibody summary

  • Rabbit polyclonal to Caspase-12 (NT)
  • Suitable for: ELISA,WB,IHC-P
  • Isotype: IgG
  • 100 µg
SKU: 8362parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

Caspase-12 (NT)

available sizes

100 µg

Available product – rabbit anti-Caspase-12 (NT) polyclonal antibody 8362

antibody
Tested applications
WB,IHC,IHC,ELISA
Recommended dilutions
Immunoblotting: use at 1ug/mL.

Immunohistochemistry: use at 10ug/mL.

These are recommended concentrations.

Enduser should determine optimal concentrations for their applications.

Positive control: Tissue lysate of mouse brain.
Immunogen
Peptide corresponding to aa 2-17 at the N-terminus of mouse caspase-12 (accession no. CAA73532).
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Storage buffer
PBS, pH 7.4.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Caspase-12 (CASP-12) (EC 3.4.22.-)
Gene names
Casp12,Casp12
Protein family
Peptidase C14A family
Mass
47854Da
Function
FUNCTION: Involved in the activation cascade of caspases responsible for apoptosis execution. {ECO:0000250}.
Tissues
TISSUE SPECIFICITY: Mainly expressed in skeletal muscle and lung.
Structure
SUBUNIT: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by two subunits (Potential). Interacts with TRAF2 under resting conditions; this interaction is reduced in ER stress conditions. {ECO:0000269|PubMed:11278723, ECO:0000305}.
Target Relevance information above includes information from UniProt accession : O08736
The UniProt Consortium

Data

benchmark-antibodies_anti-caspase-12_nt_antibody_8362_1.gif
Western blot analysis of caspase-12 in (A) human and (B) mouse spleen tissue lysates with caspase-12 antibody at 1 µg/mL.
benchmark-antibodies_anti-caspase-12_nt_antibody_8362_2.jpg
Immunohistochemistry of caspase-12 in human heart tissue with caspase-12 antibody at 10 µg/mL.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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