| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Caspase-12 (NT) |
| available sizes | 100 µg |
rabbit anti-Caspase-12 (NT) polyclonal antibody 8362
$445.00
Antibody summary
- Rabbit polyclonal to Caspase-12 (NT)
- Suitable for: ELISA,WB,IHC-P
- Isotype: IgG
- 100 µg
rabbit anti-Caspase-12 (NT) polyclonal antibody 8362
| antibody |
|---|
| Tested applications WB,IHC,IHC,ELISA |
| Recommended dilutions Immunoblotting: use at 1ug/mL. Immunohistochemistry: use at 10ug/mL. These are recommended concentrations. Enduser should determine optimal concentrations for their applications. Positive control: Tissue lysate of mouse brain. |
| Immunogen Peptide corresponding to aa 2-17 at the N-terminus of mouse caspase-12 (accession no. CAA73532). |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinty purifcation |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Caspase-12 (CASP-12) (EC 3.4.22.-) |
| Gene names Casp12,Casp12 |
| Protein family Peptidase C14A family |
| Mass 47854Da |
| Function FUNCTION: Involved in the activation cascade of caspases responsible for apoptosis execution. {ECO:0000250}. |
| Tissues TISSUE SPECIFICITY: Mainly expressed in skeletal muscle and lung. |
| Structure SUBUNIT: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by two subunits (Potential). Interacts with TRAF2 under resting conditions; this interaction is reduced in ER stress conditions. {ECO:0000269|PubMed:11278723, ECO:0000305}. |
| Target Relevance information above includes information from UniProt accession : O08736 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of caspase-12 in (A) human and (B) mouse spleen tissue lysates with caspase-12 antibody at 1 µg/mL. |
 |
| Immunohistochemistry of caspase-12 in human heart tissue with caspase-12 antibody at 10 µg/mL. |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
|---|
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
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| No results found | |||
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