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rabbit anti-BCMA polyclonal antibody 4802

$445.00

Antibody summary

  • Rabbit polyclonal to BCMA
  • Suitable for: ELISA,WB,IHC-P,IF
  • Isotype: IgG
  • 100 µg
SKU: 4802parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

B-Cell Maturation protein (BCMA)

available sizes

100 µg

Available product – rabbit anti-BCMA polyclonal antibody 4802

antibody
Tested applications
WB,IHC,IHC,ICC/IF,ELISA
Recommended dilutions
Western Blot: Use at 2-5 ug/ml. A band of approximately 27 kD is detected using K562 cell lysate as a Positive control.
Immunogen
A synthetic peptide corresponding to the carboxy terminus of human BCMA.
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
Store at 4°C; stable for one year
Storage buffer
PBS, pH 7.4.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269)
Gene names
TNFRSF17,TNFRSF17 BCM BCMA
Mass
20165Da
Function
FUNCTION: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}.
Subellular location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures.
Tissues
TISSUE SPECIFICITY: Expressed in mature B-cells, but not in T-cells or monocytes.
Structure
SUBUNIT: Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. {ECO:0000269|PubMed:12721620, ECO:0000269|PubMed:15542592}.
Domain
TOPO_DOM 1
Target Relevance information above includes information from UniProt accession : Q02223
The UniProt Consortium

Data

benchmark-antibodies_anti-b-cell_maturation_protein_bcma_antibody_4802_
Western blot analysis of BCMA in (A) human spleen tissue lysate, (B) K562, and (C) U937 cell lysates with BCMA antibody at 5 µg/mL.
benchmark-antibodies_anti-b-cell_maturation_protein_bcma_antibody_4802_
Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 5 µg/mL.
benchmark-antibodies_anti-b-cell_maturation_protein_bcma_antibody_4802_
Immunofluorescence of BCMA in Human Spleen tissue with BCMA antibody at 10 µg/mL.
benchmark-antibodies_anti-b-cell_maturation_protein_bcma_antibody_4802_
Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 10 µg/mL.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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