| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | B-Cell Maturation protein (BCMA) |
| available sizes | 100 µg |
rabbit anti-BCMA polyclonal antibody 4802
$445.00
Antibody summary
- Rabbit polyclonal to BCMA
- Suitable for: ELISA,WB,IHC-P,IF
- Isotype: IgG
- 100 µg
rabbit anti-BCMA polyclonal antibody 4802
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions Western Blot: Use at 2-5 ug/ml. A band of approximately 27 kD is detected using K562 cell lysate as a Positive control. |
| Immunogen A synthetic peptide corresponding to the carboxy terminus of human BCMA. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions Store at 4°C; stable for one year |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinty purifcation |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269) |
| Gene names TNFRSF17,TNFRSF17 BCM BCMA |
| Mass 20165Da |
| Function FUNCTION: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}. |
| Subellular location SUBCELLULAR LOCATION: Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures. |
| Tissues TISSUE SPECIFICITY: Expressed in mature B-cells, but not in T-cells or monocytes. |
| Structure SUBUNIT: Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. {ECO:0000269|PubMed:12721620, ECO:0000269|PubMed:15542592}. |
| Domain TOPO_DOM 1 |
| Target Relevance information above includes information from UniProt accession : Q02223 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of BCMA in (A) human spleen tissue lysate, (B) K562, and (C) U937 cell lysates with BCMA antibody at 5 µg/mL. |
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| Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 5 µg/mL. |
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| Immunofluorescence of BCMA in Human Spleen tissue with BCMA antibody at 10 µg/mL. |
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| Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 10 µg/mL. |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| Western blot IHC ICC |
Documents
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