| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | B-Cell Maturation protein (BCMA) |
| available sizes | 100 µg |
rabbit anti-BCMA polyclonal antibody 4802
$445.00
Antibody summary
- Rabbit polyclonal to BCMA
- Suitable for: ELISA,WB,IHC-P,IF
- Isotype: IgG
- 100 µg
rabbit anti-BCMA polyclonal antibody 4802
| antibody |
|---|
| Tested applications WB,IHC,IHC,ICC/IF,ELISA |
| Recommended dilutions Western Blot: Use at 2-5 ug/ml. A band of approximately 27 kD is detected using K562 cell lysate as a Positive control. |
| Immunogen A synthetic peptide corresponding to the carboxy terminus of human BCMA. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions Store at 4°C; stable for one year |
| Storage buffer PBS, pH 7.4. |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269) |
| Gene names TNFRSF17,TNFRSF17 BCM BCMA |
| Mass 20165Da |
| Function FUNCTION: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}. |
| Subellular location SUBCELLULAR LOCATION: Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures. |
| Tissues TISSUE SPECIFICITY: Expressed in mature B-cells, but not in T-cells or monocytes. |
| Structure SUBUNIT: Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. {ECO:0000269|PubMed:12721620, ECO:0000269|PubMed:15542592}. |
| Involvement in disease DISEASE: Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2. {ECO:0000269|PubMed:1396583}. |
| Target Relevance information above includes information from UniProt accession: Q02223 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of BCMA in (A) human spleen tissue lysate, (B) K562, and (C) U937 cell lysates with BCMA antibody at 5 µg/mL. |
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| Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 5 µg/mL. |
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| Immunofluorescence of BCMA in Human Spleen tissue with BCMA antibody at 10 µg/mL. |
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| Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 10 µg/mL. |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
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