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rabbit anti-APRIL (ED) polyclonal antibody 4051

$445.00

Antibody summary

  • Rabbit polyclonal to APRIL (ED)
  • Suitable for: ELISA,WB
  • Isotype: Whole IgG
  • 100 µg
SKU: 4051parent Category: Tags: , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
host

rabbit

isotype

IgG

clonality

polyclonal

concentration

1 mg/mL

applications

ICC/IF, WB

reactivity

APRIL (ED)

available sizes

100 µg

Available product – rabbit anti-APRIL (ED) polyclonal antibody 4051

antibody
Tested applications
WB,ELISA
Recommended dilutions
Immunoblotting: use at 5-10 ug/mL. A band of ~27kDa is detected.
Immunogen
Peptide corresponding to aa 50-100 of human APRIL.
Size and concentration
100µg and lot specific
Form
liquid
Storage Instructions
This antibody is stable for three months at 4°C and at least one year at -20°C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles.
Storage buffer
PBS, 0.02% NaN3.
Purity
peptide affinty purifcation
Clonality
polyclonal
Isotype
IgG
Compatible secondaries
goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863
goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371
goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715
goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control
Rabbit polyclonal - Isotype Control
target relevance
Protein names
Tumor necrosis factor ligand superfamily member 13 (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD antigen CD256)
Gene names
TNFSF13,TNFSF13 APRIL TALL2 ZTNF2 UNQ383/PRO715
Protein family
Tumor necrosis factor family
Mass
27433Da
Function
FUNCTION: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. {ECO:0000269|PubMed:10973284}.
Subellular location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11571266}.
Tissues
TISSUE SPECIFICITY: Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Structure
SUBUNIT: Homotrimer. {ECO:0000305}.
Post-translational modification
PTM: The precursor is cleaved by furin. {ECO:0000269|PubMed:11571266}.
Target Relevance information above includes information from UniProt accession : O75888
The UniProt Consortium

Data

benchmark-antibodies_anti-april_ed_antibody_4051_1.jpg
Western blot analysis of APRIL expression in K562 cells with APRIL antibody at (A) 5 and (B) 10 µg/mL.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

pmidtitleauthorscitation

Protocols

relevant to this product
Western blot
IHC
ICC

Documents

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