| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | rabbit |
| isotype | IgG |
| clonality | polyclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | APRIL (ED) |
| available sizes | 100 µg |
rabbit anti-APRIL (ED) polyclonal antibody 4051
$445.00
Antibody summary
- Rabbit polyclonal to APRIL (ED)
- Suitable for: ELISA,WB
- Isotype: Whole IgG
- 100 µg
rabbit anti-APRIL (ED) polyclonal antibody 4051
| antibody |
|---|
| Tested applications WB,ELISA |
| Recommended dilutions Immunoblotting: use at 5-10 ug/mL. A band of ~27kDa is detected. |
| Immunogen Peptide corresponding to aa 50-100 of human APRIL. |
| Size and concentration 100µg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for three months at 4°C and at least one year at -20°C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Storage buffer PBS, 0.02% NaN3. |
| Purity peptide affinity purification |
| Clonality polyclonal |
| Isotype IgG |
| Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720 |
| Isotype control Rabbit polyclonal - Isotype Control |
| target relevance |
|---|
| Protein names Tumor necrosis factor ligand superfamily member 13 (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD antigen CD256) |
| Gene names TNFSF13,TNFSF13 APRIL TALL2 ZTNF2 UNQ383/PRO715 |
| Protein family Tumor necrosis factor family |
| Mass 27433Da |
| Function FUNCTION: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. {ECO:0000269|PubMed:10973284}. |
| Subellular location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11571266}. |
| Tissues TISSUE SPECIFICITY: Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
| Structure SUBUNIT: Homotrimer. {ECO:0000305}. |
| Post-translational modification PTM: The precursor is cleaved by furin. {ECO:0000269|PubMed:11571266}. |
| Target Relevance information above includes information from UniProt accession: O75888 |
| The UniProt Consortium |
Data
 |
| Western blot analysis of APRIL expression in K562 cells with APRIL antibody at (A) 5 and (B) 10 µg/mL. |
FAQ & Publications
Frequently Asked Questions
What are the recommended applications and dilutions for the rabbit anti-APRIL (ED) polyclonal antibody 4051?
This antibody is suitable for ELISA and Western blot applications. For immunoblotting, it is recommended to use the antibody at a concentration of 5-10 µg/mL, where a band of approximately 27 kDa can be detected.
How should the rabbit anti-APRIL (ED) polyclonal antibody 4051 be stored to maintain stability?
The antibody is stable for three months when stored at 4°C and for at least one year at -20°C. It is advised to store the antibody in appropriate aliquots to avoid multiple freeze-thaw cycles.
What is the immunogen used to generate the rabbit anti-APRIL (ED) polyclonal antibody 4051?
The immunogen is a peptide corresponding to amino acids 50-100 of human APRIL.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot IHC ICC |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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