rabbit anti-Adenovirus polyclonal antibody 4715

rabbit anti-Adenovirus polyclonal antibody 4715

antibody
Tested applications WB,IHC,IHC,ICC/IF,IP
Recommended dilutions Immunoblotting: use at 1:500-1:1,000.
Immunogen Peptide corresponding to amino acids 255-264 of the 34 kD fiber knob protein of adenovirus 3.
Size and concentration 100µg and lot specific
Form liquid
Storage Instructions This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Storage buffer PBS, pH 7.4
Purity immunogen affinty purifcation
Clonality polyclonal
Isotype IgG
Compatible secondaries goat anti-rabbit IgG, H&L chain specific, peroxidase conjugated, conjugated polyclonal antibody 9512 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody 2079 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody 7863 goat anti-rabbit IgG, H&L chain specific, Cross Absorbed polyclonal antibody 2371 goat anti-rabbit IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1715 goat anti-rabbit IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1720
Isotype control Rabbit polyclonal - Isotype Control

target relevance
Structure Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system.
Biotechnology Direct and indirect detection methods are used for the diagnosis of Adenovirus infectons. Due to the variety of clinical symptoms, which may be caused by Adenoviruses, serological investigations have become important for the differential diagnosis of respiratory tract infections.
Involvement in disease Adenoviruses are dsDNA viruses with icosahedral symmetry and a diameter of 90 to 100 nm. They belong to the family of Adenoviridae and were discovered in isolates from adenoids. Approximately 50 subtypes have been identified as human pathogens, with subtypes 1 to 8, 40 and 41 occuring most frequently. Adenoviruses are responsible for a wide range of different diseases. In most cases, infections present with ocular, respiratory or gastrointestinal manifestations. Additionally, urethral infections, as well as hepatitis and meningoencephalitis are possible. Keratoconjunctivitis epidemica is a particularly significant ocular nosocomial infection. Patients with weakened immune systems are particularly susceptible to serious complications following infection with Adenoviruses, e.g. Acute Respiratory Distress Syndrome (ARDS). Sequelae may include persistent bronchitis, joint pain, dilative cardiomyopathy, type 1 diabetes and hearing deficits.