mouse anti-NeuN monoclonal antibody (2Q158) 9018

$100.00 – $2,600.00

Antibody summary

Mouse monoclonal to NeuN
Suitable for: WB, ICC/IF, IHC
Reacts with: human, mouse, rat, rabbit
Isotype: IgG1
100 µg, 25 µg, 1 mg

SKU: 9018parent Categories: antibody, cell marker Tag: NeuN

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	1 mg/mL
applications	ICC/IF, IHC, WB
available sizes	1 mg, 100 µg, 25 µg

mouse anti-NeuN monoclonal antibody (2Q158) 9018

antibody
Database link: human A6NFN3 mouse Q8BIF2
Tested applications WB,IHC,IHC,ICC/IF
Recommended dilutions WB: 1:500-1:1000 IF/IHC 1:5000-1:10000
Immunogen Purified cell nuclei from mouse brain
Size and concentration 100µg and 1 mg/mL
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Storage buffer PBS, 0.1% NaN₃
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal - Isotype Control

target relevance
NeuN, also known as Fox-3 or RBFOX3, is a well-established neuronal marker widely used in neuroscience research. It is a nuclear protein that is selectively expressed in post-mitotic neurons, making it an essential tool for identifying and characterizing neuronal populations in various tissues and experimental models. NeuN immunohistochemistry, facilitated by specific antibodies targeting NeuN, allows researchers to visualize and quantify neuronal cell bodies, providing valuable insights into neuronal distribution, density, and morphology. This marker is particularly valuable for studying neurodevelopment, neurodegenerative diseases, and neuronal plasticity in response to different experimental conditions or treatments. Moreover, NeuN antibodies have proven instrumental in identifying and differentiating neurons from other cell types, such as glial cells, in complex neural tissues. Click for more on: cell markers and NeuN
Protein names RNA binding protein fox-1 homolog 3 (Fox-1 homolog C) (Neuronal nuclei antigen) (NeuN antigen)
Gene names RBFOX3,RBFOX3
Mass 33873Da
Function Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
Subellular location Nucleus Cytoplasm Note=Largely restricted to neuronal nuclei. However, significant cytoplasmic localization in neurons from brains from HIV-infected individuals with cognitive impairment.
Target Relevance information above includes information from UniProt accession: A6NFN3
The UniProt Consortium

Data

https://benchmarkantibodies.com/wp-content/uploads/2024/04/9018_1.webp

IHC-P analysis of rat cerebellum tissue using NeuN antibody.Immunoreactivity is seen as nuclear staining in the neurons in the granular layer. Antigen retireval : Citrate Buffer, pH 6.0 Dilution : 1:100

https://benchmarkantibodies.com/wp-content/uploads/2024/04/9018_2.webp

IHC-P analysis of mouse brain tissue (dentate gyrus and subventricular zone) using NeuN antibody. Red : Primary antibody Green : BrdU

https://benchmarkantibodies.com/wp-content/uploads/2024/04/9018_3.webp

IHC-P analysis of mouse brain tissue (dentate gyrus and subventricular zone) using NeuN antibody.Red : Primary antibody Green : BrdU Antigen retireval : Citrate Buffer, pH 6.0

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.