| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | 1 mg/mL |
| applications | ICC/IF, WB |
| reactivity | Clostridium tetani Toxin |
| available sizes | 1 mg |
mouse anti-Clostridium tetani Toxin monoclonal antibody (B417M) 7004
$9,999.00
Antibody summary
- Mouse monoclonal to Clostridium tetani Toxin
- Suitable for:
- Isotype: IgG1
- 1 mg
mouse anti-Clostridium tetani Toxin monoclonal antibody (B417M) 7004
| antibody |
|---|
| Recommended dilutions ELISAImmunoblotting A band of ~150,000 is detected. End users should determine optimal dilutions for their applications. |
| Immunogen Toxin purified from culture filtrate of C. tetani. |
| Size and concentration 1mg and lot specific |
| Form liquid |
| Storage Instructions This antibody is stable for at least one (1) year at -20° to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Storage buffer PBS, pH 7.4. |
| Purity immunogen affinty purifcation |
| Clonality monoclonal |
| Isotype IgG1 |
| Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721 |
| Isotype control Mouse monocolonal IgG1 - Isotype Control |
| target relevance |
|---|
| Protein names Tetanus toxin (EC 3.4.24.68) (Tentoxylysin) [Cleaved into: Tetanus toxin light chain (Tetanus toxin chain L); Tetanus toxin heavy chain (Tetanus toxin chain H)] |
| Gene names tetX,tetX CTC_p60 |
| Protein family Peptidase M27 family |
| Mass 150682Da |
| Function Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. |
| Catalytic activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.; EC=3.4.24.68; |
| Structure The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation. |
| Target Relevance information above includes information from UniProt accession: P04958 |
| The UniProt Consortium |
| No results found |
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
| relevant to this product |
|---|
| Western blot IHC ICC |
| # | SDS | Certificate | |
|---|---|---|---|
| Please enter your product and batch number here to retrieve product datasheet, SDS, and QC information. | |||
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.