Immunohistochemistry (IHC) : Human tonsil stained with anti-CD11c antibody using peroxidase-conjugate and DAB chromogen. Note strong membranous staining of lymphocytes.

mouse anti-CD11c monoclonal antibody (ZM103) 6057

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to CD11c
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1
Control: Tonsil, lymph node
Visualization: Membrane
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

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SKU: 6057parent Category: antibody Tags: anatomy, CD11c, General & Epithelial Markers

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-CD11c monoclonal antibody ZM103 6057

antibody
Database link: human P20702
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Tonsil, lymph node
Immunogen Recombinant human ITGAX protein fragment (aa 637-827)
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Protein names Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)
Gene names ITGAX,ITGAX CD11C
Protein family Integrin alpha chain family
Mass 127829Da
Function FUNCTION: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Subellular location SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Tissues TISSUE SPECIFICITY: Predominantly expressed in monocytes and granulocytes.
Structure SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2. {ECO:0000269\|PubMed:20033057}.
Domain DOMAIN: The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Target Relevance information above includes information from UniProt accession: P20702
The UniProt Consortium

Data

Human tonsil stained with anti-CD11c antibody using peroxidase-conjugate and DAB chromogen. Note strong membranous staining of lymphocytes.

Publications

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We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.