| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
mouse anti-Calponin-1 monoclonal antibody (ZM21) 6049
$160.00 – $528.00
Antibody summary
- Mouse monoclonal to Calponin-1
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG1
- Control: Normal breast tissue
- Visualization: Cytoplasmic
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
mouse anti-Calponin-1 monoclonal antibody ZM21 6049
| antibody |
|---|
| Database link: human P51911 |
| Tested applications IHC |
| Recommended dilutions As directed |
| Immunogen Recombinant human CNN1 protein |
| Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated |
| Form liquid |
| Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles. |
| Purity affinity purified |
| Clonality monoclonal |
| Isotype IgG1 |
| Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721 |
| Isotype control Mouse monoclonal IgG1 - Isotype Control |
| target relevance |
|---|
| Protein names Calponin-1 (Basic calponin) (Calponin H1, smooth muscle) |
| Protein family Calponin family |
| Mass 33170Da |
| Function Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). |
| Tissues Smooth muscle, and tissues containing significant amounts of smooth muscle. |
| Structure Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1. |
| Domain DOMAIN 28..131; /note="Calponin-homology (CH)"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00044" |
| Target Relevance information above includes information from UniProt accession: P51911 |
| The UniProt Consortium |
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