| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| host | mouse |
| isotype | IgG1 |
| clonality | monoclonal |
| concentration | concentrate, predilute |
| applications | IHC |
| reactivity | human |
| available size | 0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted |
mouse anti-Adenovirus monoclonal antibody (20-11 & 2-6) 6013
$160.00 – $528.00
Antibody summary
- Mouse monoclonal to Adenovirus
- Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
- Reacts with: Human
- Isotype:IgG1
- Control: Adenovirus infected tissue
- Visualization: Organisms
- 0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted
mouse anti-Adenovirus monoclonal antibody 20&11 & 2&6 6013
| target relevance |
|---|
| Structure Adenoviruses (members of the family Adenoviridae) are medium-sized (90-100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. |
| Biotechnology Direct and indirect detection methods are used for the diagnosis of Adenovirus infectons. Due to the variety of clinical symptoms, which may be caused by Adenoviruses, serological investigations have become important for the differential diagnosis of respiratory tract infections. |
| Involvement in disease Adenoviruses are dsDNA viruses with icosahedral symmetry and a diameter of 90 to 100 nm. They belong to the family of Adenoviridae and were discovered in isolates from adenoids. Approximately 50 subtypes have been identified as human pathogens, with subtypes 1 to 8, 40 and 41 occuring most frequently. Adenoviruses are responsible for a wide range of different diseases. In most cases, infections present with ocular, respiratory or gastrointestinal manifestations. Additionally, urethral infections, as well as hepatitis and meningoencephalitis are possible. Keratoconjunctivitis epidemica is a particularly significant ocular nosocomial infection. Patients with weakened immune systems are particularly susceptible to serious complications following infection with Adenoviruses, e.g. Acute Respiratory Distress Syndrome (ARDS). Sequelae may include persistent bronchitis, joint pain, dilative cardiomyopathy, type 1 diabetes and hearing deficits. |
Data
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| Human lung stained with anti-Adenovirus antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of adenovirus infected pneumocytes . |
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| IHC |
Documents
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| Please enter your product and batch number here to retrieve - product datasheet, SDS, and QC information. | |||
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