| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Human Borrelia IgM |
| species reactivity | B. burgdorferi sensu stricto, B. garinii, B. afzelii, B. spielmanii and B. bavariensis |
| applications | Lateral flow (dipstick) |
| assay type | Indirect & qualitative |
| available sizes | 20 test kits |
Human Borrelia IgM Lateral flow dipstick kit 4273
$487.00
Summary
- Mikrogen diagnostik lateral flow device (dipstick) for research use (RUO)
- Human Borrelia IgM Lateral flow dipstick kit 4273
- Suitable for IgM detection
- Ready-to-use
- 20 tests
Human Borrelia IgM Lateral flow dipstick kit 4273
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| Assay type Sandwich assay, lateral flow (dipstick) | ||||||||||||||||||
| Research area Infectious Disease | ||||||||||||||||||
| Sample type Serum, plasma, whole blood | ||||||||||||||||||
Components
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| Storage Store at 2-8°C. | ||||||||||||||||||
| Additional information Mikrogen recomLine Borrelia Tests Mikrogen recomLine Borrelia Tests are serological, qualitative in vitro tests with recombinantly produced, highly specific and immunodominant Borrelia antigens. All specific antibodies against all known Lyme disease-causing Borrelia species (B. burgdorferi sensu stricto, B. garinii, B. afzelii, B. spielmanii, and B. bavariensis) can be detected on one test strip. The recomLine Borrelia tests are used to confirm the results of screening enzyme immunoassays. Advantages
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| target relevance |
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| Organism Borrelia burgdorferi |
| Structure and strains Borrelia burgdorferi is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato. The complex currently comprises 20 accepted and 3 proposed genospecies.B. burgdorferi sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America. Borrelia species are Gram-negative. |
| Disease Pathogens Borrelia burgdorferi is the infectious agent of Lyme-Borreliosis. B. burgdorferi sensu stricto, B. garinii, B. afzelii and B. spielmanii are the most important human pathogens of the genospecies Borrelia burgdorferi sensu lato. All four species are distributed throughout Europe in temperate climate zones. Reservoirs for the bacteria include a variety of mammals, particularly mice. The bacteria are transmitted to human hosts by infected ticks. Lyme-Borreliosis is a multisystemic disease. Dermal manifestations with Erythema migrans (EM) as a characteristic symptom of early disease are displayed by 70 to 90 % of infected persons. In addition to non-specific symptoms, in particular neurological disorders, e. g. Morbus Bannwarth, may be observed between a few weeks and several months post infection as signs of a systemic disease with single or multiple organ involvement. Development of late-stage symptoms may occur up to several years after the tick bite and are characterized by dermatological diseases (Acrodermatitis chronica athrophicans), diseases of the joints (Lyme-Arthritis), and neurological diseases (chronical encephalomyelitis). |
| Detection and diagnosis Due to the complexity of the clinical picture and the generally unspecific symptoms, serology is the appropriate method to ensure an optimal diagnosis. It is recommended to adopt a logical step-wise approach for serological diagnosis, initially using a sensitive screening assay with subsequent confirmation by another specific test. |
Publications
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| 4273 protocol |
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